Author(s):
Rushikesh Bachhav, Mayur Bhamare, Rutuja Deore, Piyush Bachhav, Dhiraj Gavali, Khemchand Surana, Sunil Mahajan
Email(s):
rbachhav2001@gmail.com
DOI:
10.52711/2231-5691.2025.00036
Address:
Rushikesh Bachhav, Mayur Bhamare, Rutuja Deore, Piyush Bachhav, Dhiraj Gavali, Khemchand Surana, Sunil Mahajan
1Department of Pharmaceutical Quality Assurance, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik.
2Department of Pharmaceutical Chemistry, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik.
3Department of Pharmaceutics, SSS’s Divine College of Pharmacy, Nampur Road, Satana, Nashik.
*Corresponding Author
Published In:
Volume - 15,
Issue - 2,
Year - 2025
ABSTRACT:
Microneedle technology is an innovative approach to transdermal drug delivery that addresses several limitations of traditional drug administration methods. By enabling minimally invasive, painless drug delivery through the skin, microneedles enhance patient compliance while maintaining drug efficacy and bioavailability. This review explores the underlying principles, various types, and fabrication techniques of microneedles, alongside their advantages and limitations. Current challenges, including material selection, scalability, and regulatory hurdles, are discussed. Applications across vaccines, systemic drug delivery, and cosmetic therapies highlight the transformative potential of microneedle technology in revolutionizing therapeutic strategies. Future advancements could further improve precision and broaden its clinical adoption.
Cite this article:
Rushikesh Bachhav, Mayur Bhamare, Rutuja Deore, Piyush Bachhav, Dhiraj Gavali, Khemchand Surana, Sunil Mahajan. Microneedle Technology for Transdermal Drug Delivery: A Comprehensive Review. Asian Journal of Pharmaceutical Research. 2025; 15(2):223-6. doi: 10.52711/2231-5691.2025.00036
Cite(Electronic):
Rushikesh Bachhav, Mayur Bhamare, Rutuja Deore, Piyush Bachhav, Dhiraj Gavali, Khemchand Surana, Sunil Mahajan. Microneedle Technology for Transdermal Drug Delivery: A Comprehensive Review. Asian Journal of Pharmaceutical Research. 2025; 15(2):223-6. doi: 10.52711/2231-5691.2025.00036 Available on: https://asianjpr.com/AbstractView.aspx?PID=2025-15-2-21
REFERENCE:
1. Gupta A. Systematic Approach to Novel Drug Delivery System. 1st ed. A and V Publications; 2019. Available from: https://anvpublication.org/About_Book.aspx?BID=18621211839190219
2. Asian Journal of Research in Chemistry. Pulmonary drug delivery system: Advancements and prospects in systemic delivery. A and V Publications; 2023. https://anvpublication.org/Journals/HTMLPaper.aspx?Journal=Asian+Journal+of+Research+in+Chemistry%3BPID%3D2010-3-4-36
3. Advances in hydrotropic solubilization techniques for poorly soluble drugs. Asian Journal of Research in Pharmaceutical Sciences. A and V Publications. Available from: https://anvpublication.org
4. Strategies for formulating gastro-retentive drug delivery systems. A and V Publications; 2022. Available from: https://anvpublication.org
5. Novel trends in parenteral drug delivery systems. Asian Journal of Research in Chemistry. A and V Publications; 2023. Available from: https://anvpublication.org
6. Biopharmaceutical aspects of nano drug delivery systems. A and V Publications; 2022. Available from: https://anvpublication.org
7. Recent advancements in aerosol-based drug delivery technology. Asian Journal of Research in Pharmaceutical Sciences. A and V Publications. Available from: https://anvpublication.org
8. Microsphere technology for targeted drug delivery. Asian Journal of Research in Chemistry. A and V Publications. Available from: https://anvpublication.org
9. Oro-dispersible tablet formulations: Current developments. Asian Journal of Research in Pharmaceutical Sciences. A and V Publications. Available from: https://anvpublication.org
10. Advances in controlled-release formulations for systemic drug delivery. Asian Journal of Recearch in Chemistry. A and V Publications. Available from: https://anvpublication.org
11. Surana KR, Ahire ED, Keservani RK, Tripathi M, Bharti SK. Chhattisgarh Journal of Science and Technology.
12. Surana, K.R., Ahire, E.D., Keservani, R.K., and Kesharwani, R.K. (Eds.). (2024). Preventive and Therapeutic Role of Vitamins as Nutraceuticals (1st ed.). Apple Academic Press. https://doi.org/10.1201/9781003414025.
13. Aakash Bairagi, Ashish Jain, Akhlesh K. Singhai. Dissolving Microneedles Drug Delivery System: A Comprehensive Review. Research Journal of Pharmaceutical Dosage Forms and Technology. 2024; 16(3):268-4. doi: 10.52711/0975-4377.2024.00042.
14. Yeu-Chun Kim, Jung-Hwan Park, Mark R, Prausnitz. Microneedles for drug and vaccine delivery. Adv Drug Deliv Rev. 2012; 64(14): 1547-1568.
15. Shayan Fakhraei Lahiji, Youseong Kim, Geonwoo Kang Suyong Kim, Seunghee Lee, Hyungil Jung. Tissue Interlocking Dissolving Microneedles for Accurate and Efficient Transdermal Delivery of Biomolecules. J. Bio.Sci. 2019; 21(3): 211223.
16. Shayan Fakhraei Lahiji, Youseong Kim, Geonwoo Kang, Suyong Kim, Seunghee Lee, Hyungil Jung. Tissue Interlocking Dissolving Microneedles for Accurate and Efcient Transdermal Delivery of Biomolecules. Scientific Reports. 2019; 9: 7886.
17. Bariya, S.H., et al. Microneedles: an emerging transdermal drug delivery system. Journal of Pharmacy and Pharmacology. 2012; 64(1): 11-29.