A Review- Nanosuspension Technology in Drug Delivery System

Sarika V. Khandbahale

doi:10.5958/2231-5691.2019.00021.2

Asian Journal of Pharmaceutical Research

ISSN

2231-5691 (Online)
2231-5683 (Print)

Submit Article

A Review- Nanosuspension Technology in Drug Delivery System

Author(s): Sarika V. Khandbahale

Email(s): sarikakhandbahale76@gmail.com

DOI: 10.5958/2231-5691.2019.00021.2

Address: Sarika V. Khandbahale
R. G. Sapkal Institute of Pharmacy, Anjaneri, Nashik
*Corresponding Author

Published In: Volume - 9, Issue - 2, Year - 2019

View HTML

View PDF

ABSTRACT:
Solubility is the crucial factor for drug effectiveness, independence of the route of administration. Large proportions of newly discovered drugs are water insoluble, and therefore poorly bioavailable contributing to deserted development effort. These so-called 'Brickellia' candidates can now be delivered by formulating them into Nanosuspension. Nanosuspension technology solved the problem of drugs which are poorly aqueous soluble and less bioavailability. Stability and bioavailability of the drugs can be improved by the Nanosuspension technology. Preparation of Nanosuspension is simple and applicable to all drugs which are aqueous insoluble. Nanosuspensions are prepared by using wet mill, high pressure homogenizer, emulsion-solvent evaporation, melt emulsification method and super critical fluid techniques. Nanosuspension can be prepared by using stabilizers, organic solvents and other additives such as buffers, salts, polyols, osmogent and cryoprotectant. Nanosuspensions can be delivered by oral, parenteral, pulmonary and ocular routes. Nanosuspensions can also be used for targeted drug delivery when incorporated in the ocular inserts and mucoadhesive hydrogels.

Keywords:

Cite this article:
Sarika V. Khandbahale. A Review- Nanosuspension Technology in Drug Delivery System. Asian J. Pharm. Res. 2019; 9(2): 130-138. doi: 10.5958/2231-5691.2019.00021.2

Cite(Electronic):
Sarika V. Khandbahale. A Review- Nanosuspension Technology in Drug Delivery System. Asian J. Pharm. Res. 2019; 9(2): 130-138. doi: 10.5958/2231-5691.2019.00021.2 Available on: https://asianjpr.com/AbstractView.aspx?PID=2019-9-2-12

Recomonded Articles:

Sublingual Tablets - An Updated Review

Author(s): Ashok Thulluru, Nawaz Mahammed, C. Madhavi, K. Nandini, S. Sirisha, D. Spandana

DOI: 10.5958/2231-5691.2019.00016.9 Access: Open Access Read More

Self-nano Emulsifying Drug Delivery System (SNEDDS): Future Aspects

Author(s): Hiral A. Makadia, Ami Y. Bhatt, Ramesh B. Parmar, Ms. Jalpa S. Paun, H.M. Tank

DOI: Access: Open Access Read More

A Review on Microsphere and it’s Application

Author(s): Kaustubh V. Gavali, Manohar D. Kengar, Kiran V. Chavan, Vaishnavi P. Anekar, Naziya I. Khan

DOI: 10.5958/2231-5691.2019.00020.0 Access: Open Access Read More

The Review on The Nasal Drug Delivery

Author(s): Prajapati M., Mandloi R., Pillai S, Birla N.

DOI: 10.5958/2231-5691.2020.00021.0 Access: Open Access Read More

Review on Solubility Enhancement Techniques

Author(s): B.A. Bhairav, J.K. Bachhav, R.B. Saudagar

DOI: 10.5958/2231-5691.2016.00025.3 Access: Open Access Read More

Study of Different Granulation Processes during Formulation Development, Evaluation, Characterization of Granules and Capsule Formulations

Author(s): Hemant Patel

DOI: Access: Open Access Read More

A Review- Nanosuspension Technology in Drug Delivery System

Author(s): Sarika V. Khandbahale

DOI: 10.5958/2231-5691.2019.00021.2 Access: Open Access Read More

Design, Development and Evaluation of Enteric Coated Tablets of Glimepiride

Author(s): Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum

DOI: 10.5958/2231-5691.2017.00024.7 Access: Open Access Read More

A Review on New Herbal Remedies for treatment of Mouth Ulcer

Author(s): Rina G. Maskare, Ayush P. Agrawal, Mayuri S. Pal, Jidnyasa R. Yerne, Megham Chaudhri, Anup R. Bawankar, Gaytri B. Sonkusre

DOI: 10.52711/2231-5691.2022.00025 Access: Open Access Read More

Formulation and Evaluation of Cinitapride Controlled Release Tablets

Author(s): Mercy Mathew, Ravikumar, Simila Madathil, Anju Govind, Narayana Swamy VB

DOI: 10.5958/2231-5691.2016.00015.0 Access: Open Access Read More

Microspheres by Spray Drying: An Approach to Enhance Solubility of Bicalutamide

Author(s): Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum

DOI: 10.5958/2231-5691.2017.00028.4 Access: Open Access Read More

Formulation and Evaluation of Immediate Release Tablet of Efavirenz by Micellar Solubilization Technique

Author(s): Snehal B. Kulkarni, M. M. Bari,S. D. Barhate, Ashutosh Tripath

DOI: 10.5958/2231-5691.2019.00003.0 Access: Open Access Read More

Design and evaluation of fast dissolving oral films of Zolpidem by solvent casting method

Author(s): Dasari Nirmala, Swapna Nandhini, M. Sudhakar

DOI: 10.5958/2231-5691.2016.00012.5 Access: Open Access Read More

Niosome: a Novel Drug Delivery System

Author(s): Kshitij B. Makeshwar, Suraj R. Wasankar

DOI: Access: Open Access Read More

Formulation and Evaluation of Controlled Release Matrix Tablets of Labetalol HCl

Author(s): Niyaz Kavugoli, Ravikumar, Narayanaswamy VB

DOI: 10.5958/2231-5691.2016.00018.6 Access: Open Access Read More

A Review: Dry Emulsion

Author(s): Vidya Dange , Shubhangi Shid, C.S. Magdum ,S.K. Mohite, M.M. Nitalikar

DOI: 10.5958/2231-5691.2015.00032.5 Access: Open Access Read More

Formulation and Evaluation of Fast Dissolving Tablets of Doxazosin Mesylate

Author(s): Mukul Ahmed, Ravikumar, Narayanaswamy VB, Injamamul Haque, Mohibul Hoque

DOI: 10.5958/2231-5691.2016.00020.4 Access: Open Access Read More

Protective effect of Pueraria tuberosa Linn. in arsenic induced nephrotoxicity in rats.

Author(s): V. Uma Rani, M. Sudhakar, A. Ramesh

DOI: 10.5958/2231-5691.2017.00003.X Access: Open Access Read More

Mouth Dissolving Tablet: A Novel Drug Delivery System

Author(s): Davesh S. Jire, Nitin S. Gosavi, Roshan B. Badhe, Dipak H. Jagdale

DOI: 10.52711/2231-5691.2021.00033 Access: Open Access Read More

Formulation and Characterization of Metformin Hydrochloride Floating Tablets

Author(s): Ashok A. Hajare, Vrushali A. Patil

DOI: Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available
DOI: 10.5958/2231–5691