Author(s): Atoussi Ouidad, Chetehouna Sara, Derouiche Samir

Email(s): Email ID Not Available

DOI: 10.5958/2231-5691.2020.00017.9   

Address: Atoussi Ouidad1, Chetehouna Sara1, Derouiche Samir1,2
1Department of Cellular and Molecular Biology, Faculty of Natural Science Sand Life, University of El Oued, El-Oued 39000, Algeria.
2Laboratory of Biodiversity and Application of Biotechnology in the Agricultural Field, University of El Oued, El-Oued 39000, Algeria.
*Corresponding Author

Published In:   Volume - 10,      Issue - 2,     Year - 2020


ABSTRACT:
The aim of this study is to use the purslan (Portulacae oleracea L) leaves aqueous extract in order to prepare copper nanoparticles and to explore antioxidant and anti-inflammatory activity of aqueous extract of P.oleracea L and CuNPs. The nanoparticles were characterized from structural and morphological point of view by using analytical techniques such as: UV-Vis spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscopy (SEM). Antioxidant activity of purslane and CuNPs was studied done FRAP assay also the anti-inflammatory and hemolysis essay were studies. The acute toxicity test was applied in Wistar albino rats. Obtain results show that the SEM analysis revealed that the particle size was found to be ranging under 46 nm. On the other hand, the copper nanoparticles and purslan possessed the reducing capacity when IC50 value was 68,316 µg/ml and 79,675 µg/ml respectively, the anti-inflammatory ability while IC50 value was 77,503 µg/ml and 60,727 µg/ml respectively. In this study, the toxicity test showed no mortality or behavioral change up to 20 mg / kg of albino Wistar rats CuNPs. We concluded that Portulaca oleracea L has potential properties as biocatalyst or natural stabilizers for CuNPs synthesis. Each CuNPs as P.oleracea L leaves extract were have a reducing and anti-inflammatory capacity which can be protect the cells against the degenerative effects of Reactive Oxygen Species (ROS).


Cite this article:
Atoussi Ouidad, Chetehouna Sara, Derouiche Samir. Biological properties and Acute Toxicity Study of Copper oxide nanoparticles prepared by aqueous leaves extract of Portulaca oleracea (L). Asian J. Pharm. Res. 2020; 10(2):89-94. doi: 10.5958/2231-5691.2020.00017.9


Recomonded Articles:

Author(s): Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum

DOI: 10.5958/2231-5691.2017.00028.4         Access: Open Access Read More

Author(s): S.K. Purohit, R. Solanki, V. Mathur, M. Mathur

DOI:         Access: Open Access Read More

Author(s): AK Meena, MM Rao, RP Meena, P Panda, Renu

DOI:         Access: Open Access Read More

Author(s): Jaseela KP, Anjan Kumar, Veeresh Babu. D, Narayana Swamy V.B

DOI: 10.5958/2231-5691.2016.00014.9         Access: Open Access Read More

Author(s): Naidu Narapusetty, O. Sivaiah, B. Balanasaraiah, M. Haranadhbabu, B. Prasad, B. Hosanna Crown, Ch. M. M. Prasada Rao

DOI: 10.5958/2231-5691.2017.00015.6         Access: Open Access Read More

Author(s): Prathap Kumar Kothapalli, Jagadeesh. S. Sanganal, N.B. Shridhar

DOI:         Access: Open Access Read More

Author(s): Debarshi Kar Mahapatra, Ruchi S. Shivhare, Pranesh Kumar

DOI: 10.5958/2231-5691.2018.00002.3         Access: Open Access Read More

Author(s): V Jhansipriya Marabathuni, K. Mariyamma, K. Sravani, S. Ramaiah, P. Ravindra, R. Srihari

DOI: 10.5958/2231-5691.2017.00026.0         Access: Open Access Read More

Author(s): Venkateshwarlu Goli, Kanakam Vijay Bhaskar, Sravan Prasad Macharla, Jimmidi.Bhaskar, P. Suvarna Devi, T. Ramchander

DOI:         Access: Open Access Read More

Author(s): Ganesh Akula, Rangu Nirmala, CH. Shanthipriya, S. Rohini Reddy, A. Jaswanth

DOI: 10.5958/2231-5691.2017.00010.7         Access: Open Access Read More

Author(s): Varsha A. Dighe, Rohini R. Pujari

DOI: 10.5958/2231-5691.2017.00004.1         Access: Open Access Read More

Author(s): Uma Sankar Gorla,. M. Savithri, G.S.N. Koteswara Rao,. Y. Niharika, . P. Devi Sree Sathya, . V. Harika

DOI: 10.5958/2231-5691.2018.00006.0         Access: Open Access Read More

Author(s): Prakash Goudanavar, Doddayya Hiremath, Spandana D. , S. R. Reddy

DOI:         Access: Open Access Read More

Author(s): Mr. Bhushan P. Gayakwad, . Shashikant D. Barhate, Prafull P. Patil, . Mayur S. Jain

DOI: 10.5958/2231-5691.2018.00009.6         Access: Open Access Read More

Author(s): Ghanshyam Dhalendra, Trilochan Satapathy, Amit Roy

DOI:         Access: Open Access Read More

Author(s): Muhammed Shakkeel K.V, Anjan Kumar, Veeresh Babu. D, Narayana Swamy V.B

DOI: 10.5958/2231-5691.2015.00021.0         Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5691 


Recent Articles




Tags