Author(s): Firoj A. Tamboli*, Harinath N. More

Email(s): firojtamboli143@gmail.com , firoj.tamboli@bharatividyapeeth.edu

DOI: 10.5958/2231-5691.2015.00028.3   

Address: Firoj A. Tamboli*, Harinath N. More
Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur -416013
*Corresponding Author

Published In:   Volume - 5,      Issue - 4,     Year - 2015


ABSTRACT:
The objective of this study was to investigate the ant proliferative activity of the successive solvent extract of leaves of plant of Barleria gibsoni Dalz. against MDA MB 4355 (Human breast cancer) and Hep G2 (Liver cancer cell line). 5 fluorouracil was given as reference drug. The leaves of plant were dried in shade and they were powdered and extracted with different solvents extract like petroleum ether, chloroform, acetone, ethyl acetate, ethanol. The preliminary phytochemical tests were done. Pet ether, chloroform extract of leaves showed that significant ant proliferative effects were obtained against MDA MB 4355 (Human breast cancer) by SRB assay method and ethanol extract of leaves showed moderate activity against Hep G2 (Liver cancer cell line) by MTT assay method due to presence of phytoconstituents present in the plant.


Cite this article:
Inhibitory Effects of Successive Solvant Extracts of Barleria gibsoni Dalz. on the Proliferation of MDA MB 4355 (Human Breast Cancer) and Hep G2 (Liver Cancer Cell line). Asian J. Pharm. Res. 5(4): 2015; 183-185. doi: 10.5958/2231-5691.2015.00028.3


Recomonded Articles:

Author(s): Mohite M S, Shelar P A, Raje V N., Babar S. J., Sapkal R. K.

DOI:         Access: Open Access Read More

Author(s): Vidya Raju, Jasmine Joy Bell, Merlin. N. J, Shaiju S. Dharan

DOI: 10.5958/2231-5691.2017.00033.8         Access: Open Access Read More

Author(s): Elumalai A., Prakash Yoganandam G.

DOI:         Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5691 


Recent Articles




Tags