Author(s): Md. Khalequeuzzaman, Shakib Al Hasan, Masoumul Haque, Rozina Parul, Mohammad Rezwanur Alam

Email(s): sobujph@gmail.com

DOI: 10.52711/2231-5691.2023.00017   

Address: Md. Khalequeuzzaman1*, Shakib Al Hasan1, Masoumul Haque1, Rozina Parul1, Mohammad Rezwanur Alam2
1Department of Pharmacy, Gono Bishwabidyalay, Mirzanagar, Savar, Dhaka, Bangladesh.
2Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh.
*Corresponding Author

Published In:   Volume - 13,      Issue - 2,     Year - 2023


ABSTRACT:
The present study was undertaken to investigate the antioxidant and anti inflammatory activity of ethanolic extract of Glochidion acuminatum leaves. Ethanolic extract of the leaves of the plant was subjected to various in-vitro assays. Antioxidant potential was tested through total phenol content, total flavonoid content, DPPH free radical scavenging capacity and total anti-oxidant capacity assay. Anti-inflammatory activity was tested against the denaturation of protein. Glochidion acuminatum exhibited good antioxidant potential on total phenol content assay, TPC as GAE was 507.24±19.48mg/gm. It showed remarkable antioxidant potential on total flavonoid content assay, TFC as QE was 486.28±16.44mg/gm. In DPPH free radical scavenging assay IC50 value was 14.97µg/ml while for standard ascorbic acid it was found to be 8.87µg/ml which express potent antioxidant activity. It also showed excellent antioxidant potential on total antioxidant capacity assay, TAC as AAE was 712.5±5.89µg/ml. Anti-inflamatory assay showed that the plant leaves extract possess very good anti-inflamatory potential. These effects may be due to the presence of different phytoconstituents present in the extract. Further studies are required to evaluate these effects and due to the findings which warrants further more sophisticated research.


Cite this article:
Md. Khalequeuzzaman, Shakib Al Hasan, Masoumul Haque, Rozina Parul, Mohammad Rezwanur Alam. Evaluation of Antioxidant and Anti-inflamatory Activity of Ethanolic Extract of Glochidion acuminatum Leaves. Asian Journal of Pharmaceutical Research. 2023; 13(2):87-1. doi: 10.52711/2231-5691.2023.00017

Cite(Electronic):
Md. Khalequeuzzaman, Shakib Al Hasan, Masoumul Haque, Rozina Parul, Mohammad Rezwanur Alam. Evaluation of Antioxidant and Anti-inflamatory Activity of Ethanolic Extract of Glochidion acuminatum Leaves. Asian Journal of Pharmaceutical Research. 2023; 13(2):87-1. doi: 10.52711/2231-5691.2023.00017   Available on: https://asianjpr.com/AbstractView.aspx?PID=2023-13-2-3


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DOI: 10.5958/2231–5691 


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