Nalla Priyanka, M. Srikanth, G. Raveendra Babu, M. Sowjanya, V. Ramya Sri, M. Vasanthi, K. Sri Lakshmi Bhargavi, Y. Tirupathaiah, K. Mohana Sri Vasavi, N. Raviteja
Nalla Priyanka1*, M. Srikanth2, G. Raveendra Babu3, M. Sowjanya4, V. Ramya Sri1, M. Vasanthi1, K. Sri Lakshmi Bhargavi1, Y. Tirupathaiah1, K. Mohana Sri Vasavi1, N. Raviteja1
1Department of Pharmaceutical Chemistry, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh.
2Department of Pharmacognosy, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh.
3Department of Pharmaceutical Analysis, A.K.R.G. College of Pharmacy, Nallajerla, W.G. Dist., Andhra Pradesh.
4Department of Chemistry, Vijaya Teja Degree College, Addanki - 523201, Andhra Pradesh.
Volume - 12,
Issue - 4,
Year - 2022
Anthocephalus cadamba, Rubiaceae, is a medicinal herb of great importance for traditional applications against several disease kinds. Because of the range of compounds, the genus Anthocephalus is regarded as one of the most significant genus utilised in many medical systems. The plant was chemically investigated for its phytoconstituents in the current analysis, Anthocephalus cadamba. The results for steroids, flavanoids, tannins and glycosides were shown to be positive. Bacterial species, such as Staphylococcus aureus, Bacillus subtiliis and Escherichia coli, have been moderately actively monopolised. Antifungal activity at doses of 100mg/ml, 300mg/ml with fungal organisms, was observed in the ethanol leaves extract. Plant ethanol extract had a substantial impact on the hydrogen peroxide radical activity of scavenging and less effects than the standard of nitric oxide radical activity.
Cite this article:
Nalla Priyanka, M. Srikanth, G. Raveendra Babu, M. Sowjanya, V. Ramya Sri, M. Vasanthi, K. Sri Lakshmi Bhargavi, Y. Tirupathaiah, K. Mohana Sri Vasavi, N. Raviteja. In-vitro Screening of Anti-microbial, Anti-fungal and Anti-oxidant activities of Ethanolic leaf extract of Anthocephalus cadamba. Asian Journal of Pharmaceutical Research 2022; 12(4):275-0. doi: 10.52711/2231-5691.2022.00044
Nalla Priyanka, M. Srikanth, G. Raveendra Babu, M. Sowjanya, V. Ramya Sri, M. Vasanthi, K. Sri Lakshmi Bhargavi, Y. Tirupathaiah, K. Mohana Sri Vasavi, N. Raviteja. In-vitro Screening of Anti-microbial, Anti-fungal and Anti-oxidant activities of Ethanolic leaf extract of Anthocephalus cadamba. Asian Journal of Pharmaceutical Research 2022; 12(4):275-0. doi: 10.52711/2231-5691.2022.00044 Available on: https://asianjpr.com/AbstractView.aspx?PID=2022-12-4-3
1. Gontijo DC, Nunes LG, Farias LM, Duarte MG, Carvalho AF, Fietto LG, Leite JP. Assessment of the phenolic content, mutagenicity and genotoxicity of ethanolic extracts of stem bark and leaves from Strychnospseudoquina A. St.-hil. Drug ChemToxicol 2018; 10: 1-7.
2. Nostro A, Germanò MP, D'angelo V, Marino A, Cannatelli MA. Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity. Lett Appl Microbiol 2000; 30: 379-384.
3. Choudhary R, Tandon RV. Consumption of functional food and our health concerns. Pak J Physiol 2009; 5: 76-83.
4. Shahrbandy K, Hosseinzadeh R. In vitro antioxidant activity of Polygoniumlyrcanicum, Centaureaedepressa, Sambusebulus, Menthe spicata and Phytolaceae Americana. Pak J BiolSci 2007; 10: 637-640.
5. Saeed N, Khan MR, Shabbir M. Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilisleptophylla L. BMC Complement Altern Med 2012; 12: 221-232.
6. Song JM, Lee KH, Seong BL. Antiviral effect of catechins in green tea on influenza vírus. Antivir Res 2005; 68: 66–74.
7. Cushnie TT, Lamb AJ. Antimicrobial activity of flavonoids. Int. J. Antimicrob Agents 2005; 26: 343–356.
8. Da Silva MA, Cardoso CA, Vilegas W, Dos Santos LC. High-performance liquid chromatographic quantification of flavonoids in Eriocaulaceae species and their antimicrobial activity. Molecules 2009 ; 14: 4644-54.
9. Ferguson PJ, Kurowska E, Freeman DJ, Chambers A.F, Koropatnick DJ. A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines. J Nutr 2004; 134: 1529–1535.
10. Russo A, Cardile V, Sanchez F, Troncoso N, Vanella A, Garbarino JA. Chilean propolis: antioxidant activity and antiproliferative action in human tumor cell lines. Life Sci 2004; 76: 545–558.
11. Alam MA, Akter R, Subhan N, Rahman MM, Majumder MM, Nahar L, Sarker SD. Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba. Brazilian J Pharmacog 2008; 18: 155–9.
12. Schwikkard S, van Heerden FR. Antimalarial activity of plant metabolites. Nat Prod Rep 2002; 19: 675–692.
13. Kapil A, Koul IB and Suri OP. Antihepatotoxic effects of chlorogenic acid from Anthocephaluscadamba. Phytother Res 1995; 9: 189–193.
14. Kodangula SC, Borthakur A and Kodangala SP. Anti-inflammatory effect of the methanol extract from Anthocephalus cadamba stem bark in animal modelsa. Int J Plant Biol 2010; 1: 30–2.
15. Acharyya S, Dash GK, Mondal S and Dash SK. Studies on Glucose Lowering Efficacy of the Anthocephalus cadamba (Roxb.)Miq. roots. Int J Pharma Bio Sci 2010; 1: 1–9.
16. Verza SG, Kreinecker MT, Reis V, Henriques AT, Ortega GG. Evaluation of analytical variables of the Folin-Ciocalteu method for the quantitation of the total tannins content using a Psidiumguajava L. leaves aqueous extract as a model. Química Nova 2007; 30: 815-20.
17. Krishna Kondragunta. V, Karuppuraj. V, Perumal. K. Antioxidant activity and Folic acid content in indigenous isolates of Ganodermalucidum. Asian J. Pharm. Ana. 2016; 6(4): 213-215.
18. P. Muthukumaran, P. Padmapriya, S. Salomi, R. Umamaheshwari, P. Kalaiarasan, C. Malarvizhi. In Vitro Anti Microbial Activity of Leaf Powder. Asian J. Pharm. Res. 1(4): Oct. - Dec. 2011; Page 108-110.
19. MuthusamySenthil Kumar, SrinivasanBalachandran, ShibaniChaudhury. Influence of Incubation Temperatures on Total Phenolic, Flavonoids Content and Free Radical Scavenging Activity of Callus from Heliotropium indicum L. Asian J. Pharm. Res. 2(4): Oct. - Dec. 2012; Page 148-152.
20. Ch. Madhu, J. Swapna, K. Neelima, Monic V. Shah. A Comparative Evaluation of the Antioxidant Activity of Some Medicinal Plants Popularly Used in India. Asian J. Res. Pharm. Sci. 2(3): July-Sept. 2012; Page 98-100.
21. Konda Ravi Kumar, K.N.S. Karthik, P. Reshma Begum, Ch. M.M. PrasadaRao.Synthesis, characterization and biological evaluation of benzothiazole derivatives as potential antimicrobial and analgesic agents. Asian J. Res. Pharm. Sci. 2017; 7(2):115-119.
22. Patel D.S. Shah P. B., Managoli N. B. Evaluation of In-vitro Anti-oxidant and Free Radical Scavenging activities of Withania somnifera and Aloe vera. Asian J. Pharm. Tech. 2(4): Oct. - Dec. 2012; Page 143-147.
23. Pranita A. Argade, Mangesh A. Bhutkar, Chandrakant S. Magdum. Albizzialebbeck extract mediated synthesis of Zinc Oxide Nanoparticles and study of its In-vitro Anti-diabetic and Anti-oxidant activity. Asian J. Pharm. Tech. 2019; 9(2):93-98.
24. Balakrishnan N, Panda A B, Raj N R, Shrivastava A, Prathani R. The Evaluation of Nitric Oxide Scavenging Activity of AcalyphaIndica Linn Root. Asian J. Research Chem. 2(2): April.-June, 2009 page 148-150.
25. Ankush Garg, Radhika Maheshwari, Pooja Chawla, Shubhini A. Saraf. Free Radical Scavenging Activity of Novel 5-Substituted Arylidene-3-Substituted-Benzyl-Thiazolidine-2, 4-Diones. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 528-530.
26. Shlini P., Siddalinga Murthy K.R. Extraction of Phenolics, Proteins and Antioxidant Activity from Defatted Tamarind Kernel Powder. Asian J. Research Chem. 4(6): June, 2011; Page 936-941.