Author(s):
Satyajit Kamble, Saurabh Dhenge
Email(s):
satyajeetkamble34@gmail.com
DOI:
10.52711/2231-5691.2025.00067 
Address:
Satyajit Kamble*, Saurabh Dhenge
Student, Department of Pharmaceutics, Ashokrao Mane Institute of Pharmaceutical Sciences and Research, Save, Kolhapur, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 4,
Year - 2025
ABSTRACT:
This study examined the latest advancements in medication delivery and nanogel production. The study of herbal compounds is the focus of a field of chemistry known as phytochemistry. Plants have been used medicinally because they are the safest alternative to modern allopathic medications and contain a range of therapeutic potentials. To improve drug penetration through the topical route, herbal extract is employed to make nanoparticles; the formulation with the best trapping efficacy is chosen to prepare nanogel. The utilization of herbal substances has aided in the creation of novel treatments for a range of illnesses. Using nanogels is the most logical way to improve bioavailability and treat skin diseases. The benefits of phytoconstituents or plant extract-loaded nanogels on a variety of skin disorders, such as infections, acne, and aging, have been shown both in vitro and in vivo.
Cite this article:
Satyajit Kamble, Saurabh Dhenge. Formulation Strategies and Evaluation of Antifungal Herbal Nanogels: A Comprehensive Review. Asian Journal of Pharmaceutical Research.2025; 15(4):431-9. doi: 10.52711/2231-5691.2025.00067
Cite(Electronic):
Satyajit Kamble, Saurabh Dhenge. Formulation Strategies and Evaluation of Antifungal Herbal Nanogels: A Comprehensive Review. Asian Journal of Pharmaceutical Research.2025; 15(4):431-9. doi: 10.52711/2231-5691.2025.00067 Available on: https://asianjpr.com/AbstractView.aspx?PID=2025-15-4-13
REFERENCES:
1. Azad Khana, Nayyar Parvez, Santosh Kumar Joshi, Alok Pratap Singh. Herbal Based Nanogel Formulation for Skin Disease - Optimization and Evaluation Parameters. 2023: 1.
2. Bongomin F, Gago S, Oladele RO, Denning DW. Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision. Journal of Fungi. 2017 3: 57.
3. Rodrigues ML, Nosanchuk JD. Fungal Diseases as Neglected Pathogens. 2020: 3.
4. Dr. Bitar. Canadian Family Physician. 1973: 65.
5. Cuggino JC, Blanco ERO, Gugliotta LM, Alvarez Igarzabal CI, Calderón M. Crossing Biological Barriers with Nanogels to Improve Drug Delivery Performance. Journal of Controlled Release. 2019: 221–246.
6. Suhail M, Rosenholm JM, Minhas MU, Badshah SF, Naeem A, Khan KU, Fahad M. Nanogels as Drug-Delivery Systems: A Comprehensive Overview. Therapeutic Delivery. 2019: 697–717.
7. Li Y, Maciel D, Rodrigues J, Shi X, Tomás H. Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery. Chemical Reviews. 2015: 8564–8608.
8. Sultana F, Manirujjaman, Imran-Ul-Haque M, Arafat M, Sharmin S. An Overview of Nanogel Drug Delivery System. Journal of Applied Pharmaceutical Science. 2013; 3: 96–105.
9. Sultana F, Manirujjaman, Imran-Ul-Haque M, Arafat M, Sharmin S. An Overview of Nanogel Drug Delivery System. Journal of Applied Pharmaceutical Science. 2013; 3: 96–100.
10. Patel H, Patel J. Nanogel as a Controlled Drug Delivery System. International Journal of Pharmaceutical Sciences Review and Research. 2010; 4: 37–41.
11. Wani T, Rashid M, Kumar M, Chaudhari S, Kumar P, Mishra N. Targeting Aspects of Nanogels: An Overview. International Journal of Pharmaceutical Sciences and Nanotechnology. 2014; 7: 26.12.
12. Kapadi S, Gadhel L, Talele S, Chaudhari G. Recent Trend in Nano pharmaceuticals: An Overview. World Journal of Pharmaceutical Research. 2015; 4: 553–566.
13. Singh N, Gill V, Gill P. Nanogel-Based Artificial Chaperone Technology: An Overview. American Journal of Advanced Drug Delivery. 2013; 1(3): 271–276.
14. Rossetti H, Albizzati D, Alfano M. Decomposition of Formic Acid in a Water Solution Employing the Photo-Fenton Reaction. Ind Eng Chem Res. 2002: 41–44.
15. Zarekar NS, Lingayat VJ, Pande VV. Nanogel as a Novel Platform for Smart Drug Delivery System. Nanoscience and Nanotechnology Research. 2017; 4: 25–31.
16. Sindhu RK, Gupta R. Modern Herbal Nanogels: Formulation, Delivery Methods, and Applications. 2022; 34.
17. Mota AH, Sousa A, Figueira M, Amaral M, Sousa B, Rocha J, Fattal E, Almeida AJ. Natural-Based Consumer Health Nanoproducts: Medicines, Cosmetics, and Food Supplements. Handbook of Functionalized Nanomaterials for Industrial Applications. 2020: 527–578.
18. Kishimura A, Koide A, Osada K, Yamasaki Y, Kataoka K. Encapsulation of Myoglobin in Pegylated Polyion Complex Vesicles Made from a Pair of Oppositely Charged Block Ionomers: A Physiologically Available Oxygen Carrier. Angew Chem Int Ed. 2007: 6085–6088.
19. Yallapu MM, Jaggi M, Chauhan SC. Design and Engineering of Nanogels for Cancer Treatment. Drug Discov. 2011: 457–463.
20. Ezhilararasan D, Lakshmi T, Raut B. Novel Nano-Based Drug Delivery Systems Targeting Hepatic Stellate Cells in the Fibrotic Liver. J. Nanomaterial. 2021:23.
21. Lozinsky V. Synthesis and Structure-Property Relationships of Cryogels. Adv. Polym. Sci. 2014; 263: 103.
22. Pandey A, Tripathi S. Concept of Standardization, Extraction, and Pre-Phytochemical Screening Strategies for Herbal Drug. J Pharmacogn Phytochem. 2014: 115.
23. Sasidharan S, Chen Y, Saravanan D, Sundram KM, Yoga Latha L. Extraction, Isolation and Characterization of Bioactive Compounds from Plant Extracts. Afr J Tradit Complement Altern. 2011; 8: 1–10.
24. Altemimi A, Lakhssassi N, Baharlouei A, Watson DG, Lightfoot DA. Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts. 2017; 6: 42.
25. Abubakar AR, Haque M. Preparation of Medicinal Plants: Basic Extraction and Fractionation Procedures for Experimental Purposes. 2020: 8–9.
26. Mishra KK, Kaur CD, Sahu AK, Panik R, Kashyap P, Mishra SP, Dutta S. Medicinal Plants Having Antifungal Properties. 2020: 3–42.
27. Varma K, Amalraj A. Herbs, Spices and Their Roles in Nutraceuticals and Functional Foods, 2023: 1–2.
28. Mao QQ, Xu XY, Cao SY, Gan RY, Corke H, Beta T, Li HB. Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe). 2019: 1–2.
29. Avocado History. Avocados from Mexico. 2017: 18
30. Avocado. Fruits of Warm Climates, Purdue University. 2016: 27: 4.
31. Chen H, Morrell PL, Ashworth V, de la Cruz M, Clegg MT. Tracing the Geographic Origins of Major Avocado Cultivars. Journal of Heredity. 1093: 56–65.
32. Storey WB. What Kind of Fruit is the Avocado? California Avocado Society. 1973: 70–71.
33. Anjarwalla P, Jamnadass R, Ofori DA, Stevenson PC. Pesticidal Plant Leaflet Tithonia diversifolia (Hemsley) A. Gray. Research Art Article of Tithonia Diversifolia. 2014: 1.
34. Preissel U, Preissel HG. Brugmansia and Datura: Angel's Trumpets and Thorn Apples. Buffalo, New York: Firefly Books, Issue 2002, Page No. 120–123.
35. Bitencourt MAO, Lima MCJ, Torres-Rêgo M, Fernandes JM, DaSilva-Júnior AA, Tambourgi DV, Zucolotto SM, Fernandes-Pedrosa MF. Neutralizing Effects of Mimosa tenuiflora Extracts Against Inflammation Caused by Tityus serrulatus Scorpion Venom. Biomed Research International. 2014: 2.
36. Basso J, Miranda A, Nunes S, Cova T, Sousa J, Vitorino C, Pais A. Hydrogel-Based Drug Delivery Nanosystems for the Treatment of Brain Tumors. Gels. 2018; 4: 62.
37. Patra JK, Das G, Fraceto LF, Campos EVR, Rodriguez-Torres MDP, Acosta-Torres LS, Diaz-Torres LA, Grillo R, Swamy MK, Sharma S, et al. Nano-Based Drug Delivery Systems: Recent Developments and Future Prospects. J. Nanobiotechnol. 2018; 16: 71.
38. Sindhu RK, Gupta R, Wadhera G, Kumar P. Modern Herbal Nanogels: Formulation, Delivery Methods, and Applications. Faculty of Health Sciences, School of Therapeutic Sciences, University of the Witwatersrand, Johannesburg, Page No. 2–3.
39. Sayantan M, Pragati T. Recent Advances in Nanogels in Drug Delivery Systems. Int. J. Pharm. Sci. Nanotechnol. 2021: 5278–5286.
40. Sindhu RK, Gupta R, Wadhera G, Kumar P. Modern Herbal Nanogels: Formulation, Delivery Methods, and Applications. Faculty of Health Sciences, School of Therapeutic Sciences, University of the Witwatersrand, Johannesburg, Page No. 3–4.
41. Muniraj SN, Yogananda R, Nagaraja TS, Bharathi DR. Preparation and Characterization of Nanogel Drug Delivery System Containing Clotrimazole: An Anti-Fungal Drug. Indo-American J Pharmaceutical Research. 2020; 7: 1013–1022.
42. Muniraj SN, Yogananda R, Nagaraja TS, Bharathi DR. Preparation and Characterization of Nanogel Drug Delivery System Containing Clotrimazole: An Anti-Fungal Drug. Indo-American J Pharmaceutical Research. 2020; 10(7): 1013–1022.
43. Fathima R, Karumakar G, Mamatha S, Viswanath K, Tebilla Chetsiya KB. Nanogel: A Future Drug Delivery Tool. International Journal Pharmaceutical Sciences Review and Research. 2022: 31–32.
44. Mahaparale S, Kotkhane M. A Review on: Nanogels. Latin American Journal of Pharmacy. 2023; 3: 219.
45. Jadhan P, Harsulakar AA. A Review On: Herbal Nanogel. Indo-American Journal of Pharmaceutical Sciences. 2022: 25–26.