T. Panneer Selvam, G. Saravanan, C. R. Prakash, P. Dinesh Kumar
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T. Panneer Selvam*1, G. Saravanan2, C. R. Prakash3, P. Dinesh Kumar4
1Department Pharmaceutical Chemistry, Srinivas College of Pharmacy, Mangalore -574142, Karnataka, India
2Medicinal Chemistry Research Lab, Bapatla College of Pharmacy, Bapatla-522101, Andhrapradesh, India.
3Department Pharmaceutical Chemistry, DCRM Pharmacy College, Inkollu-523167, Andhrapradesh, India.
4Department of Pharmaceutics, Rahul Institute of Pharmaceutical Science & Research, Chirala-523157, Andhra Pradesh, India.
Volume - 1,
Issue - 4,
Year - 2011
A series of 1-(4-substitutedphenyl)-3-phenyl-1H-pyrazole-4-carbaldehyde 4a-e has been synthesized and tested for their anti-inflammatory and analgesic activities. Formation of the pyrazole derivatives was achieved by treating vilsmeier-haack reagent. The newly synthesized compounds were evaluated for their anti-inflammatory and analgesic activities compared to indomethacin, flufenamic acid and diazepam as standard drugs. The detailed synthesis, spectroscopic and toxicity data are reported.
Cite this article:
T. Panneer Selvam, G. Saravanan, C. R. Prakash, P. Dinesh Kumar. Microwave-Assisted Synthesis, Characterization and Biological Activity of Novel Pyrazole Derivatives. Asian J. Pharm. Res. 1(4): Oct. - Dec. 2011; Page 126-129.