Author(s):
Aniket Patil, Abhijeet Kulkarni, Satyajit Kamble, Samruddhi Kamerkar, Sanika Kharat, Sana Sutar, Shital Shinde
Email(s):
satyajeetkamble34@gmail.com
DOI:
10.52711/2231-5691.2025.00005 
Address:
Aniket Patil, Abhijeet Kulkarni, Satyajit Kamble*, Samruddhi Kamerkar, Sanika Kharat, Sana Sutar, Shital Shinde
Department of Pharmaceutics, Ashokrao Mane Institute of Pharmaceutical Sciences and Research, Save, Kolhapur, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 1,
Year - 2025
ABSTRACT:
A careful selection of essential oils with well-known soothing and digestive effects went into the produce of this Ayurvedic topical preparation for the management of infant dyspepsia. Due to their long history of easing digestive problems and enhancing gastrointestinal comfort, essential oils were selected. Topical Ayurvedic preparations for the treatment of dyspepsia can alleviate symptoms by directly addressing the abdominal region. For external use on the belly, ingredients like ajwain, fennel, and ginger can be utilized as an oil. Due to their well-known digestive qualities, these organic components can help reduce indigestion, bloating, and pain in infants. These oils were carefully combined in the right amounts to prepare a pleasing blend that successfully treats the symptoms of infantile dyspepsia. Factors like skin irritation, skin penetration, and safety for usage in infants were taken into account during the formulation process. To improve skin penetration and ensure a gentle application on the infant’s sensitive skin, carrier oils were added to the composition. The combination of essential oils acts in concert to lessen bloating, ease reflux episodes, and ease gastrointestinal pain. Without the use of harsh chemicals or artificial additives, the formulation provides a gentle and holistic approach to managing newborn dyspepsia by utilizing the natural healing capabilities of these essential oils.
Cite this article:
Aniket Patil, Abhijeet Kulkarni, Satyajit Kamble, Samruddhi Kamerkar, Sanika Kharat, Sana Sutar, Shital Shinde. Design and Development of Ayurvedic Topical Formulation for the Management of Dyspepsia in Infant. Asian Journal of Pharmaceutical Research. 2025; 15(1):22-8. doi: 10.52711/2231-5691.2025.00005
Cite(Electronic):
Aniket Patil, Abhijeet Kulkarni, Satyajit Kamble, Samruddhi Kamerkar, Sanika Kharat, Sana Sutar, Shital Shinde. Design and Development of Ayurvedic Topical Formulation for the Management of Dyspepsia in Infant. Asian Journal of Pharmaceutical Research. 2025; 15(1):22-8. doi: 10.52711/2231-5691.2025.00005 Available on: https://asianjpr.com/AbstractView.aspx?PID=2025-15-1-5
REFERENCES:
1. Dibyajyoti Saha, Swati Paul, S. M. Zahid Hosen, Talha Bin Emran and Zahed Bin Rahim on Role of Ayurvedic formulation in digestion Department of Pharmacy, BGC Trust University Bangladesh, Chittagong August 2012.
2. Shital. S. Shinde, Ashwini. G. Sonavane, T. D. Dudhgaonkar, A. R. Dhole, C. S. Magdum. International Journal of Scientific Research in Science and Technology. 2016. (2)2: 269-274.
3. Shivam. M. Goswami, Vishnu M. Patel, A.P.M.CA Brief Review on Topical Drug Delivery System and Gel. 2022; 7(1); Jan-Feb: 271-278.
4. Nidhi Shah, Anuja Rana, Shuchi Mitra, Usha Sharma, Khem Chand Sharma. A Comprehensive Exploration of Topical Dosage Form in Ayurveda: A Review. Feb, 2024; 7(2): 19-25.
5. Sharadha M, Gowda D V, Vishal Gupta N, Akhila A R Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru - 570015, Karnataka, India oct 2019
6. Lekshmy M, Shuchi Mitra, Usha Sharma and Khem Chand Sharma A review on advanced forms of ayurvedic lepa kalpana (Topical Application). 2021; 7(9).
7. Chua AS, Reassessment of functional dyspepsia: a topic review: World J Gastroenterol. 2006; 12: 2656-2659.
8. Barazandeh F, Dyspepsia: a common riddle in practice, both for patients and doctors: Middle East J Dig Dis. 2010; 2: 3-4.
9. Stanghellini V, Chan FKL, Hasler WL et al. Gastroduodenal disorders. Gastroenterology. 2016; 150(6): 1380–1392.
10. Mahadeva S, Goh K-L. Epidemiology of functional dyspepsia: a global perspective. World J Gastroenterol. 2006; 12(17): 2661–2666.
11. El-Serag HB, Talley NJ. Systemic review: the prevalence and clinical course of functional dyspepsia. Aliment Pharmacol Ther. 2004; 19(6): 643–654
12. Castillo EJ, Camilleri M, Locke GR et al. A community-based, controlled study of the epidemiology and pathophysiology of dyspepsia. Clin Gastroenterol Hepatol. 2004; 2(11): 985–996.
13. Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, un investigated dyspepsia: a meta-analysis. Gut. 2015; 64(7): 1049–1057.
14. Zagari RM, Fuccio L, Bazzoli F. Investigating dyspepsia. BMJ. 2008; 337: a1400
15. Ford AC, Marwaha A, Lim A, Moayyedi P. What is the prevalence of clinically significant endoscopic findings in subjects with dyspepsia? Systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2010; 8: 830–837.
16. Kimberly N. Harer, MD, ScM, and William L. Hasler, MD Gastroenterology and Hepatology Volume 16, Issue 2 February 2020
17. Dr. Jadhao Ujwala Ashokrao, Dr. Hedaoo N. R., Dr. Gandhi P. K., Dr. Lagad C. E.and Dr. Ingole R. K. A brief review on essential oil. 2019; 5(12): 51-56.
18. Jeet Gandhi, Disha Suthar, Dr. Hetal Patel, Dr. Pragna Shelat, Dr. Punit Parejiya Insights on Preformulation studies for potential of Essential oil of Syzygium aromaticum as an active for Dermal TherapeuticsResearch J. Pharm. and Tech. 2020; 13(6).
19. Dr. Shivendra Kumar Dwivedi, Practical Lab Manual of Pharmaceutical Organic Chemistry - I First Edition-2020
20. Vinny Chanchlani and Priya Goyal, Lavika Sharma, Sakshi Sharma and Harshita Nathawat review on digital ph meter volume 11, issue 12 December 2023
21. Jeet Gandhi, Disha Suthar, Dr. Hetal Patel, Dr. Pragna Shelat, Dr. Punit Parejiya Research on Insights on Preformulation studies for potential of Essential oil of Syzygium aromaticum as an active for Dermal Therapeutics 20 Jan 2020
22. Abi Munajad, Cahyo Subroto and Suwarno review on Fourier Transform Infrared (FTIR) Spectroscopy Analysis of Transformer Paper in Mineral Oil-Paper Composite Insulation under Accelerated Thermal Aging 4 February 2018
23. R.O.A. Adelagun, E. P. Berezi, J. O. Fagbemi, O. J. Igbaro, F. E. Aihkoje, O. Ngana, G., Osondu and M. S. Garba, evaluation of level of rancidity of edible oil in some fried snacks food. 2023; 48(1)154 – 161.
24. A. A. Hajare A Practical Book of Physical Pharmaceutics-II First Edition Jan 2019
25. Muhammad Hamza Ashfaq, Amna Siddique, Sammia Shahid A Review on Antioxidant Activity of Cinnamon zeylanicum Asian Journal of Pharmaceutical Research. 2021; 11(2): April - June,
26. V.Prema, K. Mohamed Rizwan, S. Tamilarasan An Overview on Neonatal Jaundice Asian Journal of Pharmaceutical Research. 2023; 13(3).
27. Amitder Nath Chatterjee Role of Antifungal Therapy in Treating different Types of Fungal Infections and it’s Future: A Systematic Review Asian Journal of Pharmaceutical Research. 2023; 13(2)
28. Rakesh K. Joshi, Bipin C. Joshi, Mukul K. Sati Chemical and Chemotaxonomic Aspects of Some Aromatic and Medicinal Plants Species from Utrrakhand: A Review Asian J. Pharm. Tech. 2014; 4(3): 157-162.
29. Hepsi Bai. J, End of Life / Palliative Care in Newborns and Infants Asian J. Nursing Edu. and Research. 2015; 5(2).
30. Mohammed Abdel-Hamid and Leyla H. Sharaf Use of Stable Labeled Internal Standards LC-MS/MS Method for the Detection and Confirmation of Inherited Metabolic Diseases in Sick Infants Research J. Pharm. And Tech. 2012; 5(6).
31. Shruthi Chandrasekaran Geetha. R.V Antibacterial Activity of the Three Essential Oils on Oral Pathogens An In-vitro Study Research J. Pharm. And Tech. 2014; 7(10).
32. Mansi Chitkara, Rakesh K. Sindhu, Inderbir Singh, Deepak Kumar, Inderjit Singh Sandhu, Sandeep Arora Formulation and Evaluation of Essential Oils based Liquid Herbal Hand Wash Research J. Pharm. And Tech. 2020;13(4).
33. Saumya Subramanian, Padmaja Ananth Shenoy, Vasudev Pai Antimicrobial activity of some Essential oils and Extracts from Natural sources on Skin and Soft tissue infection causing microbes: An In-vitro Study Research J. Pharm. And Tech. 2021; 14(7).
34. Haitham Qaralleh, Khaled M Khleifat, Ali M Khlaifat, Muhamad Al-limoun, Nafe M Al-Tawarah1, Amir Menwer Alhroob4, Ahmad B Alsaudi Chemical Composition, Antioxidant and Inhibitory Effect of Cupressus Sempervirens Essential Oils and Methanolic Extract on Beta-lactamase Producing Isolates Research J. Pharm. And Tech. 2021; 14(9).