Author(s): Zainab A. Bagalkote, Ganesh Gajeli

Email(s): bagalkotezainab123@gmail.com

DOI: 10.52711/2231-5691.2021.00030   

Address: Zainab A. Bagalkote*, Dr. Ganesh Gajeli
D.S.T.S. Mandal’s College of Pharmacy, Solapur.
*Corresponding Author

Published In:   Volume - 11,      Issue - 3,     Year - 2021


ABSTRACT:
Objective: A new, simple, sensitive, precise, reproducible UV visible spectrophotometric method was developed for the estimation of Carbimazole in Tablet dosage form. Methods: The UV spectrum of Carbimazole in methanol and distilled water (30:70) showed ? max at 289.6nm. Beer’s law is valid in the concentration range of 10-50µg/ml. This method was validated for linearity, accuracy, precision, ruggedness and robustness. Results: The method has demonstrated excellent linearity over the range of 10-50µg/ml with the regression equation y = 0.0232x + 0.0466, and regression coefficient i.e, r2= 0.9992 moreover, the method was found to be highly sensitive with LOD (1.818µg/ml) and LOQ (5.509µg/ml). Conclusion: From the results it can be concluded that the given method can be successfully applied for assay of Carbimazole in Tablet dosage form.


Cite this article:
Zainab A. Bagalkote, Ganesh Gajeli. UV Spectrophotometric Method Development and Validation of Carbimazole in Bulk and Tablet Dosage form. Asian Journal of Pharmaceutical Research. 2021; 11(3):163-6. doi: 10.52711/2231-5691.2021.00030

Cite(Electronic):
Zainab A. Bagalkote, Ganesh Gajeli. UV Spectrophotometric Method Development and Validation of Carbimazole in Bulk and Tablet Dosage form. Asian Journal of Pharmaceutical Research. 2021; 11(3):163-6. doi: 10.52711/2231-5691.2021.00030   Available on: https://asianjpr.com/AbstractView.aspx?PID=2021-11-3-4


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DOI: 10.5958/2231–5691 


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