Author(s): Girish Pai K., Vamshi Krishna T., Lalit Kumar, M. Sreenivasa Reddy, G. Shreenidhi, A. Praneeth Reddy

Email(s): girish.pai@manipal.edu

DOI: Not Available

Address: Girish Pai K.*, Vamshi Krishna T., Lalit Kumar, M. Sreenivasa Reddy, G. Shreenidhi, A. Praneeth Reddy
Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2013


ABSTRACT:
The objective of this study was to compare the physical parameters of uncoated tablets of Amlodipine Besylate in strip, blister and alu-alu type of primary packages under prescribed storage conditions recommended by the manufacturer, and finally to conclude the efficient primary package. The strip, blister and alu-alu packaging of antihypertensive drug Amlodipine Besylate 5mg of the same formulation type (uncoated tablets) were randomly collected from the pharmacy outlets. These tablets were subjected for various physical parameters testing like description (appearance), hardness, weight variation, friability and disintegration time. After performing Quality Control tests and comparing the results obtained, it was observed that the physical stability of the tablet has been retained very well and results were comparable in all three types of primary packages, i.e., strip, blister and alu-alu packaging. Based on supporting data we can conclude that if the formulation is stable enough, packing in aluminum strip or blister type of primary packaging shall take care of the product with respect to physical stability. Thus packing in alu – alu can be avoided which calls for additional product cost. This circumvents unnecessary cost burden on the patients and consumers. However it is better to use specifically alu-alu type of package for a sensitive product since it provides greater protection from the environmental conditions under the prescribed storage conditions recommended by the manufacturer.


Cite this article:
Girish Pai K., Vamshi Krishna T., Lalit Kumar, M. Sreenivasa Reddy, G. Shreenidhi, A. Praneeth Reddy. Comparative evaluation of the physical parameters of uncoated tablets of Amlodipine Besylate with different types of primary packaging materials. Asian J. Pharm. Res. 3(1): Jan.-Mar. 2013; Page 03-05.


Recomonded Articles:

Author(s): Mukul Ahmed, Ravikumar, Narayanaswamy VB, Injamamul Haque, Mohibul Hoque

DOI: 10.5958/2231-5691.2016.00020.4         Access: Open Access Read More

Author(s): Akhil Gupta, Anuj Mittal , Alok Kumar Gupta

DOI:         Access: Open Access Read More

Author(s): Dasari Nirmala, Swapna Nandhini, M. Sudhakar

DOI: 10.5958/2231-5691.2016.00012.5         Access: Open Access Read More

Author(s): Injamamul Haque, Ravikumar, Narayanaswamy VB, Mohibul Hoque

DOI: 10.5958/2231-5691.2016.00023.X         Access: Open Access Read More

Author(s): Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum

DOI: 10.5958/2231-5691.2017.00024.7         Access: Open Access Read More

Author(s): Sravani Koralla, Sathish Kumar Konidala, K Govinda Rao, Sheik Mobina Begum

DOI:         Access: Open Access Read More

Author(s): Girish Pai K., Vamshi Krishna T., Lalit Kumar, M. Sreenivasa Reddy, G. Shreenidhi, A. Praneeth Reddy

DOI:         Access: Open Access Read More

Author(s): Prakash Goudanavar, Doddayya Hiremath, Spandana D. , S. R. Reddy

DOI:         Access: Open Access Read More

Author(s): Ashok Thulluru, Nawaz Mahammed, C. Madhavi, K. Nandini, S. Sirisha, D. Spandana

DOI: 10.5958/2231-5691.2019.00016.9         Access: Closed Access Read More

Author(s): Sugiyartono, Tutiek Purwanti, Isnaeni, Dhenok Reso Fenda Asega

DOI:         Access: Open Access Read More

Author(s): Indu Sharma, Bharat Parashar, Hitesh Kumar Dhamija , Ritu sharma

DOI:         Access: Open Access Read More

Author(s): Jude Chigozie Ikewuchi, Catherine Chidinma Ikewuchi and Mercy Onuekwuzu Ifeanacho

DOI:         Access: Open Access Read More

Author(s): Snehal B. Kulkarni, M. M. Bari,S. D. Barhate, Ashutosh Tripath

DOI: 10.5958/2231-5691.2019.00003.0         Access: Closed Access Read More

Author(s): K. Vijaya Sri, R. Harish Kumar Reddy , R. Mahesh

DOI:         Access: Open Access Read More

Author(s): Mamatha Kola, Subharna Mallik, Pranusha Palle, Pallavi Kamarapu

DOI:         Access: Open Access Read More

Author(s): Prathibha Suvarna, Ravi Kumar, Yamunappa, Pooja Shetty, Narayana Swamy V.B.

DOI: 10.5958/2231-5691.2016.00003.4         Access: Open Access Read More

Author(s): Ikewuchi Jude C.1*, Ikewuchi Catherine C.1, Ifeanacho Mercy O.1, Igboh Ngozi M.2, Enuneku Emeke C.1 and Osayande Osazee I.1

DOI:         Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5691 


Recent Articles




Tags