Author(s): Kimmi katoch, Abhishek

Email(s): katochkimmi@gmail.com

DOI: 10.52711/2231-5691.2026.00052   

Address: Kimmi katoch*, Abhishek
Arni University, Arni School of Pharmacy, Kathgarh, (H.P).
*Corresponding Author

Published In:   Volume - 16,      Issue - 3,     Year - 2026


ABSTRACT:
One of the innovative strategies used in the pharmaceutical business to improve therapeutic advantages, such as patient compliance, formulation flexibility, and ease of dosage administration, is GRDDS. This Oral drug delivery systems and controlled release drug delivery systems, such as GRDDS, which serve as drug reservoirs and release drugs in a regulated manner over a predetermined amount of time, are the foundation of this research. Enhancing the medicine's bioavailability is the primary goal of the gastroretentive drug delivery method. The basic anatomy and physiology of the gastrointestinal tract, the requirements for a gastroretention drug, the necessity of gastro retention, the factors influencing gastroretentive time, the benefits and drawbacks of GRDDS, and recent developments in gastro-retentive drug delivery systems are all covered in this study.


Cite this article:
Kimmi katoch, Abhishek. A Review on Gastro Retentive Drug Delivery System. Asian Journal of Pharmaceutical Research. 2026; 16(3):355-2. doi: 10.52711/2231-5691.2026.00052

Cite(Electronic):
Kimmi katoch, Abhishek. A Review on Gastro Retentive Drug Delivery System. Asian Journal of Pharmaceutical Research. 2026; 16(3):355-2. doi: 10.52711/2231-5691.2026.00052   Available on: https://asianjpr.com/AbstractView.aspx?PID=2026-16-3-20


REFERENCES:
1.    Nitave SA, Patil VA, Kagalkar AA. Review on gastro retentive drug delivery system (GRDDS). Int. J. Pharm. Sci. Rev. Res. 2014; 27:90-5.
2.    Vishwakarma SK, Mishra JN, Vishwakarma DK. A Review on GRDDS Recent Advances in Drug Delivery Systems and Its Application. World Journal of Pharmaceutical Research. 2021 Jul 14; 10(11): 1159-75.
3.    Singh M, Das MK. A Comprehensive Review on Role of Natural Polymers in Gastro Retentive Drug Delivery System (GRDDS). Drug Delivery Letters. 2024 Oct 14.
4.    Tripathi J, Thapa P, Maharjan R, Jeong SH. Current state and future perspectives on gastroretentive drug delivery systems. Pharmaceutics. 2019 Apr 20;11(4):193.
5.    Kumar V, Somkuwar S, Singhai AK, Kumar V, Somkuwar S, Singhai AK. A recent update on gastro retentive drug delivery systems. GSC Biol. Pharm. Sci. 2024; 27:125-44.
6.    Dubey A, Ovais M, Bisen AC, Rajendiran A. Advancements and Challenges in Gastroretentive Drug Delivery Systems: A Comprehensive Review of Research Innovation, Technologies, and Clinical Applications. Recent Advances in Drug Delivery and Formulation. 2025 Apr 28.
7.    Ramavath VN. A review on gastro retentive drug delivery system. International Journal of Indigenous Herbs and Drugs. 2025 Aug 9:13-7.
8.    Zanke AA, Gangurde HH, Ghonge AB, Chavan PS. Recent advance in gastroretantive drug delivery system (GRDDS). Asian Journal of Pharmaceutical Research. 2022;12(2):143-9.
9.    Sharma G, Nautiyal U, Ahmad S. An overview on gastroretentive drug delivery system (GRDDS). International Journal of Health and Biological Sciences. 2019;2(2):1-8.
11.    Pawar M, Patkal R, Bhalekar P, Karad O. A Review on Gastro Retentive Drug Delivery System (GRDDS). International Journal of Scientific Research and Technology. 2025 Feb 5.
12.    Rathod HJ, Mehta DP, Yadav JS. A review on gastroretentive drug delivery systems. PharmaTutor. 2016 Jul 1;4(7):29-40.
13.    Niranjanbhai BD, Mahendrakumar VN, Surendran CS, Viral S, Upadhyay UM. Advances in grdds: raft forming system a review. Journal of Drug Delivery and Therapeutics. 2012;2(5):123-8.
14.    Bhandwalkar MJ, Dubal PS, Tupe AK, Mandrupkar SN. Review on gastroretentive drug delivery system. Asian J. Pharm. Clin. Res. 2020 Dec 7;13(12):38-45.
15.    Pachpor MS. A Systemic Review on: Formulation and Evaluation of Gastroretentive Tablet. World Journal of Pharmaceutical Sciences. 2025 Jun 14.
16.    Mandal UK, Chatterjee B, Senjoti FG. Gastro-retentive drug delivery systems and their in vivo success: A recent update. Asian journal of pharmaceutical sciences. 2016 Oct 1;11(5):575-84.
17.    Badoni A, Ojha A, Gnanarajan G, Kothiyal P. Review on gastro retentive drug delivery system. The pharma innovation. 2012 Oct 1;1(8, Part A):32.
18.    Waqar MA, Mubarak N, Khan AM, Khan R, Shaheen F, Shabbir A. Advanced polymers and recent advancements on gastroretentive drug delivery system; a comprehensive review. Journal of drug targeting. 2024 Jul 2;32(6):655-71.
19.    Laxmi KD, Sree GS, Kapileshwer H, Devi J, Sandhyaja J. A Review On Gastro Retentive Drug Delivery System (Grdds).
20.    Zaid M, Kalam I, Majaz Q. Gastro Retentive Drug Delivery System. International Journal of Research in Pharmacy and Allied Science. 2024 Nov 8;3(5):6-16.
21.    Kumar A, Kumari S, Srivastava T. A review on Gastro retentive floating drug delivery system (GRDDS). Organized by. 2018;418.
22.    Rouge, N., Buri, P., and Doelker, E. (1996). Drug absorption sites in the gastrointestinal tract and dosage forms for site-specific delivery. International Journal of Pharmaceutics, 136(1–2), 117–139.
23.    Singh, B. N., and Kim, K. H. (2000). Floating drug delivery systems: An approach to oral controlled drug delivery via gastric retention. Journal of Controlled Release, 63(3), 235–259.
24.    Streubel, A., Siepmann, J., and Bodmeier, R. (2006). Gastroretentive drug delivery systems. Expert Opinion on Drug Delivery, 3(2), 217–233.
25.    Arora, S., Ali, J., Ahuja, A., Khar, R. K., and Baboota, S. (2005). Floating drug delivery systems: A review. AAPS PharmSciTech, 6(3), E372–E390.
26.    Kagan, L., Lapidot, N., Afargan, M., and Hoffman, A. (2010). Gastroretentive dosage forms: New technologies for enhanced absorption. Current Pharmaceutical Design, 16(10), 1191–1201.
27.    Pawar, V. K., Kansal, S., Garg, G., Awasthi, R., Singodia, D., and Kulkarni, G. T. (2011). Gastroretentive dosage forms: A review with special emphasis on floating drug Delivery Systems. Drug Delivery, 18(2), 97–110.
28.    Park, K. (2014). Controlled drug delivery systems: Past forward and future back. Journal of Controlled Release, 190, 3–8.
29.    Hoffman, A. S. (2012). Hydrogels for biomedical applications. Advanced Drug Delivery Reviews, 64, 18–23.
30.    Preis, M., Woertz, C., Schneider, K., Kukawka, F., Broscheit, J., and Breitkreutz, J. (2015). 3D printing in pharmaceutical sciences: A review of the state of the art and future perspectives. Advanced Drug Delivery Reviews, 108, 39–50.
31.    Kotreka, U. K., and Adeyeye, M. C. (2011). Gastroretentive floating drug delivery systems: A review. Journal of Pharmacy Research, 4(11), 4181–4188.
32.    Jassal M, Nautiyal U, Kundlas J, Singh D. A review: Gastroretentive drug delivery system (grdds). Indian Journal of Pharmaceutical and Biological Research. 2015 Jan 1;3(1):82.

Recomonded Articles:

Author(s): Habeeb Ahmed, Mohammed Ehtesham, Nuha Rasheed , Abdul Saleem Mohammad

DOI: 10.5958/2231-5691.2017.00006.5         Access: Open Access Read More

Author(s): Ashok Thulluru, Nawaz Mahammed, C. Madhavi, K. Nandini, S. Sirisha, D. Spandana

DOI: 10.5958/2231-5691.2019.00016.9         Access: Open Access Read More

Author(s): Kaustubh V. Gavali, Manohar D. Kengar, Kiran V. Chavan, Vaishnavi P. Anekar, Naziya I. Khan

DOI: 10.5958/2231-5691.2019.00020.0         Access: Open Access Read More

Author(s): Hiral A. Makadia, Ami Y. Bhatt, Ramesh B. Parmar, Ms. Jalpa S. Paun, H.M. Tank

DOI:         Access: Open Access Read More

Author(s): Ashok B. Patel, Ashish H. Asnani, Amitkumar J. Vyas, Nilesh K. Patel, Ajay I. Patel, Arvind N. Lumbhani

DOI: 10.52711/2231-5691.2021.00034         Access: Open Access Read More

Author(s): B. Hemalatha, M. Kalpana, B. Sree Rekha, A. Varalakshmi, K. Padmalatha

DOI: 10.52711/2231-5691.2022.00041         Access: Open Access Read More

Author(s): B.A. Bhairav, J.K. Bachhav, R.B. Saudagar

DOI: 10.5958/2231-5691.2016.00025.3         Access: Open Access Read More

Author(s): Neha Meshram, Mithlesh Ojha, Ajay Singh, Amit Alexander, Ajazuddin, Mukesh Sharma

DOI: 10.5958/2231-5691.2015.00009.X         Access: Open Access Read More

Author(s): Priyanka Kusarkar, Mayuri Kupkar, Trupti Dudhgaonkar

DOI: 10.52711/2231-5691.2022.00032         Access: Open Access Read More

Author(s): Nikita R. Nikam, Rohan R. Vakhariya, Dr. C. S. Magdum

DOI: 10.5958/2231-5691.2019.00018.2         Access: Open Access Read More

Author(s): Manohar D. Kengar, Kiran K. Patole, Akshay K. Ade, Sumesh M. Kumbhar, Chetan D. Patil, Ashutosh R. Ganjave

DOI: 10.5958/2231-5691.2019.00019.4         Access: Open Access Read More

Author(s): S.C. Shivhare, U.D.Shivhare, Preeti Srivastav, K.G. Malviya

DOI:         Access: Open Access Read More

Author(s): Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum

DOI: 10.5958/2231-5691.2017.00024.7         Access: Open Access Read More

Author(s): Bansi l. Bhalodiya, Amit Kumar J. Vyas, Ajay I. Patel, Ashvin V. Dudhrejiya, Ashok B. Patel

DOI: 10.52711/2231-5691.2023.00020         Access: Open Access Read More

Author(s): A.B. Roge, P.S. Tarte, M.M. Kumare, G.R. Shendarkar, S.M. Vadvalkar

DOI:         Access: Open Access Read More

Author(s): Prajapati M., Mandloi R., Pillai S, Birla N.

DOI: 10.5958/2231-5691.2020.00021.0         Access: Open Access Read More

Author(s): Subhashis Debnath, C. Navya Yadav, N. Nowjiya, M. Prabhavathi, A. SaiKumar, P. Sai Krishna, M. Niranjan Babu

DOI: 10.5958/2231-5691.2019.00009.1         Access: Open Access Read More

Author(s): Sarika V. Khandbahale

DOI: 10.5958/2231-5691.2019.00021.2         Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5691 


Recent Articles




Tags