Author(s):
Sejal Vilas Patil, Sameer R Shaikh, Azam Z. Shaikh, Divakar R. Patil, Akash S. Jain
Email(s):
azamph46@gmail.com
DOI:
10.52711/2231-5691.2025.00034 
Address:
Sejal Vilas Patil1, Sameer R Shaikh2, Azam Z. Shaikh3, Divakar R. Patil4, Akash S. Jain5
1Student, Bachelor of Pharmacy, P.S.G.V.P.M’s College of Pharmacy, Shahada.
2Assistant Professor, Department of Pharmaceutics, P.S.G.V.P.M’s College of Pharmacy, Shahada.
3Assistant Professor, Department of Pharmaceutics, P.S.G.V.P.M’s College of Pharmacy, Shahada.
4Assistant Professor, Department of Quality Assurance, P.S.G.V.P.M’s College of Pharmacy, Shahada.
5Assistant Professor, Department of Pharmaceutics, P.S.G.V.P.M’s College of Pharmacy, Shahada.
*Corresponding Author
Published In:
Volume - 15,
Issue - 2,
Year - 2025
ABSTRACT:
Stem cell biology is an established field. Stem cells can be found in early embryos, foetuses, amniotic fluid, adult tissues, umbilical cord, blood, and the placenta. Long after birth and throughout an individual's lifespan, stem cells continue to exist in a variety of tissues. A number of bodily tissues still contain stem cells, including the skin, hair follicles, bone marrow, blood, brain, spinal cord, lining of the nose, stomach, lung, joint fluid, muscle, fat, and menstrual blood. The term "self-renewal" or "self-replication" refers to a stem cell's special capacity to duplicate itself repeatedly. The potential applications of stem cells in health and medical research are enormous. For example, our knowledge of how to control stem cell differentiation in the laboratory and our investigation of differentiation pathways provide insight into the human developmental process from embryo to adult. Controlling the proliferation of cells or tissues can be useful for a variety of purposes, including disease modelling, drug screening, and cell-based treatments. There is a lot of interest in the research of adult stem cells. Scientists and medical experts are discussing whether to use adult stem cells for transplantation in light of this revelation. We now have evidence that stem cells exist in the brain and heart. Much more research is needed to understand the biology, use, and safety of stem cells before their full therapeutic potential may be realized. The potential of stem cells for tissue regeneration and repair is enormous. Although stem cell research is moving quickly forward, numerous challenges remain before stem cells may be applied to the production of new drugs or regenerative medicine.
Cite this article:
Sejal Vilas Patil, Sameer R Shaikh, Azam Z. Shaikh, Divakar R. Patil, Akash S. Jain. Steam Cell: The Next Frontier of Medicine. Asian Journal of Pharmaceutical Research. 2025; 15(2):209-4. doi: 10.52711/2231-5691.2025.00034
Cite(Electronic):
Sejal Vilas Patil, Sameer R Shaikh, Azam Z. Shaikh, Divakar R. Patil, Akash S. Jain. Steam Cell: The Next Frontier of Medicine. Asian Journal of Pharmaceutical Research. 2025; 15(2):209-4. doi: 10.52711/2231-5691.2025.00034 Available on: https://asianjpr.com/AbstractView.aspx?PID=2025-15-2-19
REFERENCES:
1. Sachin Awasthi, R. N. Srivastava, Ajai Singh and Manoj Srivastav. Stem cell: past, present and future- a review article, Internet Journal of Medical Update. 2008; 3(1).
2. Roopa R Nadig. Stem cell therapy – hype or hope? A review. J Conserve Dent. 2009; 12(4).
3. Robert Lanza. Essentials of stem cell biology. 2007: 17-18.
4. Savneet Kaur, and Cckartha. Stem cells: concepts and prospects. Current Trends in Science. 436.
5. Elaine Fuchs and Srikala Raghavan. Nature Reviews Genetics. 2002; 199-209 doi:10.1038/nrg758.
6. Thomson et. Al. Blastocysts embryonic stem cell lines derived from human. Science. 1998; 282(5391): 1145–1147. Doi:10.1126/science.282.5391.1145.
7. Wang et al. Autologous bone marrow stem cell transplantation for the treatment of type 2 diabetes mellitus. Chin Med Journal. 2011
8. Xie et al. Human bone marrow mesenchymal stem cell differentiates into insulin-producing cells upon microenvironmental manipulation in vitro. 2009
9. Sun et al. Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitro. Chin Med Journal. 2007.
10. Salama et al. Autologous hematopoietic stem cell transplantation in 48 patients with end stage chronic liver diseases. Cell Transplant. 2010
11. Khan et al. Safety and efficacy of autologous bone marrow stem cell transplantation through hepatic artery for the treatment of chronic liver failure: a preliminary study. Transplant Proc. 2008
12. Thomas et al. Mesenchymal Stem Cells as Anti-inflammatories: Implications for Treatment of Duchenne Muscular Dystrophy. Cell Immunology. 2009
13. Helen et al. The New England Journal of Medicine). Cell Therapy for Muscular Dystrophy. 2008
14. Sen et al. Induction Therapy with Autologous Mesenchymal Stem Cells in Living-Related Kidney Transplants. JAMA. 2012
15. Tzouvelekis et al. Stem cell therapy for idiopathic pulmonary fibrosis: a protocol proposal. Journal of Translational Medicine. 2011.
16. Strauer et al. The acute and long-term effects of intracoronary Stem cell Transplantation in 191 patients with chronic heary failure: the STAR heart study. European Journal of Heart Failure. 2010
17. Rodriguez et al. Autologous stromal vascular fraction therapy for rheumatoid arthritis: rationale and clinical safety. International Archives of Medicine. 2012.
18. Dador (2010). Stem cells used to remove eye wrinkles http;//abclocal.go.com/kabc/story?section=news/health/ you healthandid=7351660
19. Sutherland H J, Eaves C J, Eaves A C, et al 1989 Blood 74 1563.
20. Hombria J C and Lovegrove B 2003 Differentiation71 461.
21. Cowan C A, Atienza J, Melton D A, et al 2005 Science309 1369.