Volume No. :   10

Issue No. :  2

Year :  2020

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Formulation and Evaluation of Bioadhesive Buccal Drug Delivery of Sumatriptan Succinate Tablets



Address:   Dr. Y. Krishna Reddy, Juveria Tasleem
Department of Pharmaceutics, Nalanda College of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana.
*Corresponding Author
DOI No: 10.5958/2231-5691.2020.00020.9

ABSTRACT:
The objective of this study was to develop effective buccal tablets of Sumatriptan Succinate. Tablets of Sumatriptan Succinate were prepared by direct compression method using bioadhesive polymers like Poloxamer188, ß-CD, HPMC K4M. Buccal tablets were prepared by taking polymers in different ratios. The formulation F9 showed maximum drug release (98.92%) in 8 hrs. It was considered as optimized formulation.
KEYWORDS:
Sumatriptan Succinate, Buccal tablets, Poloxamer188, β‐CD, HPMC K4M, in-vitro drug release.
Cite:
Dr. Y. Krishna Reddy, Juveria Tasleem. Formulation and Evaluation of Bioadhesive Buccal Drug Delivery of Sumatriptan Succinate Tablets. Asian J. Pharm. Res. 2020; 10(2):105-109.
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