Author(s): Makwana Gopal, Jain Sachin Kumar, Vengrelekar Sudha

Email(s): gopalmakwana1196@gmail.com

DOI: 10.52711/2231-5691.2023.00043   

Address: Makwana Gopal, Jain Sachin Kumar, Vengrelekar Sudha
Department of Pharmacology, Faculty of Pharmacy, Oriental University, Indore.
*Corresponding Author

Published In:   Volume - 13,      Issue - 4,     Year - 2023


ABSTRACT:
Aim: The Present studies were evaluate antianxiety activity of methanolic composite leaves extract of (Zingiber officinale, Azadirachta indica, Curcuma longa and Hibiscus rosasinesis) on administration in rats. Method: Male albino Wistar rat were taken and divided into 5 groups and each group contain 4 rats. Diazepam (1mg/kg) and composite extract (50mg/kg, 75mg/kg and 150mg/kg) were suspended in water and administrate orally. In these studies vehicle/ drugs were given 30min before exposure to experimental model such as actophometer and rotarod. C.E increase locometry actvity and time taken by rat to falling from the rod in actophometer and rotarod. The activity of rat is compared with standard drugs diazepam (1mg/kg). Result: The studied shown that at dose of 50mg/kg, 75mg/kg and 150mg/kg composite extract posse’s significant antidepressant activity.


Cite this article:
Makwana Gopal, Jain Sachin Kumar, Vengrelekar Sudha. Evaluation of antidepressant activity of Polyherbal methanolic extract of leaves of Zingiber officinale, Azadirachta indica, Curcuma longa and Hibiscus rosasinesis. Asian Journal of Pharmaceutical Research. 2023; 13(4):233-6. doi: 10.52711/2231-5691.2023.00043

Cite(Electronic):
Makwana Gopal, Jain Sachin Kumar, Vengrelekar Sudha. Evaluation of antidepressant activity of Polyherbal methanolic extract of leaves of Zingiber officinale, Azadirachta indica, Curcuma longa and Hibiscus rosasinesis. Asian Journal of Pharmaceutical Research. 2023; 13(4):233-6. doi: 10.52711/2231-5691.2023.00043   Available on: https://asianjpr.com/AbstractView.aspx?PID=2023-13-4-4


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