Schiff bases and Bicyclic derivatives comprising 1, 3, 4-thiadiazole moiety- A Review on their Pharmacological activities

Sherin A. Hameed; Joyamma Varkey; P. Jayasekhar

doi:10.5958/2231-5691.2019.00047.9

Asian Journal of Pharmaceutical Research

ISSN

2231-5691 (Online)
2231-5683 (Print)

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Schiff bases and Bicyclic derivatives comprising 1, 3, 4-thiadiazole moiety- A Review on their Pharmacological activities

Author(s): Sherin A. Hameed, Joyamma Varkey, P. Jayasekhar

Email(s): sherinirshad@gmail.com

DOI: 10.5958/2231-5691.2019.00047.9

Address: Sherin A. Hameed1, Joyamma Varkey2, P. Jayasekhar3
1College of Pharmaceutical Sciences, Govt. Medical College, Thiruvananthapuram-695011
2College of Pharmaceutical Sciences, T.D Medical College, Alappuzha-688005
3College of Pharmacy, National University of Science and Technology, Muscat, Oman
*Corresponding Author

Published In: Volume - 9, Issue - 4, Year - 2019

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ABSTRACT:
1, 3, 4-thiadiazole is a well-known heterocyclic nucleus which form an integral feature of various natural products and medicinal agents. It has enormous biological potential due to their privileged structure and is able to undergo various chemical reactions which make researcher more comfortable in drug designing. The stability of thiadiazole nucleus has inspired medicinal chemist to carryout various structural variations in the ring. This review highlights the pharmacological activity of recently synthesized Schiff bases and fused ring systems comprising1,3,4- thiadiazole moiety.

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Cite this article:
Sherin A. Hameed, Joyamma Varkey, P. Jayasekhar. Schiff bases and Bicyclic derivatives comprising 1, 3, 4-thiadiazole moiety- A Review on their Pharmacological activities. Asian J. Pharm. Res. 2019; 9(4):299-306. doi: 10.5958/2231-5691.2019.00047.9

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DOI: 10.5958/2231–5691