Author(s): Roshani Bhalerao*, Dinesh Rishipathak, Pavan Udavant, Sanjay Kshirsagar

Email(s): Email ID Not Available

DOI: 10.5958/2231-5691.2017.00041.7   

Address: Roshani Bhalerao*, Dinesh Rishipathak, Pavan Udavant, Sanjay Kshirsagar
MET’S Institute of Pharmacy, Bhujbal Knowledge City, Adgaon, Nashik-422003, Savitribai Phule Pune University, India
*Corresponding Author

Published In:   Volume - 7,      Issue - 4,     Year - 2017


ABSTRACT:
The aim of study was to synthesize a new series of Thiazolidinedione. Thiazolidinedione or glitziness forms a significant class of drug which exhibit biological activities ranging from antidiabetic, antiinflamatory, antibacterial, antifungal, antiviral, and anti-cancer. In the present study reported a systematic synthesis of thiazolidinedione. A new series of 2,4-thiazolidinedione based derivative have been synthesize by condensation of. The structure of these compounds were establish by IR and 1H NMR. These new compound (C1-C4) were evaluated for their antidiabetic activity on albino rat. Most of compound shows significant antidiabetic activity when compare with standard drug metformin.


Cite this article:
Roshani Bhalerao*, Dinesh Rishipathak, Pavan Udavant, Sanjay Kshirsagar. Synthesis and Evaluation of Antidiabetic Activity of Few 5-(4-(5-Substitutedphenyl)-1,3,4-Oxadiazlole-2-Yl) Methoxy)Benzylidene) Thiazolidine 2,4-Dione Derivatives. Asian J. Pharm. Res. 2017; 7(4): 261-264. doi: 10.5958/2231-5691.2017.00041.7


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DOI: 10.5958/2231–5691 


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