Author(s): Rutuja R Shah, Poonam J Patil, Pratibha R Adnaik, Rahul S Adnaik

Email(s): Email ID Not Available

DOI: 10.5958/2231-5691.2020.00045.3   

Address: Rutuja R Shah1*, Poonam J Patil2*, Pratibha R Adnaik1, Rahul S Adnaik1
1Anandi Pharmacy College, Kalambe-Tarfe-Kale.
2Gahlot Institute of Pharmacy, Koparkharne.
*Corresponding Author

Published In:   Volume - 10,      Issue - 4,     Year - 2020


ABSTRACT:
The most common problem in now days is related to the fungal infection. Present work was focused on developing herbal antifungal soap as of commercially available soap shows few of side effects to sensitive skin and are much costly. Presently we have used Piper betel leaf commonly known as betel leaf (khau pan) and garlic oil. The traditional Indian ayurvedic document describes several of its medicinal properties including as an effective antifungal agent. The present study was conducted to evaluate the secondary metabolite that contributes to its antifungal activity. In present work we have formulated antifungal soap of garlic oil and betel leaf extract with synergistic effect for the fungal infection. The different batches were formulated to study soap base effect in formulation and optimized batch was further used for herbal soap formulation. The formulation was evaluated and observed clear, good ability. The formulation of F3 batch shows best result of evaluation parameters as compare to F1 and F2. The optimized batch formulation of F3 showed good result. Microbial study has been done using microorganism such as Proteus vulgaris, bacillus, klebsiella pneumoniae, Staphylococcus aureus, pseudomonas aeruginosa, for measuring the effectiveness of an antimicrobial agent against fungi/bacteria grown in culture, the microorganism of the interest was swabbed uniformly across a culture plate. Then soap of 5X5 mm was placed on the surface of the agar. Then the plates were placed in the incubator for 24 hrs.


Cite this article:
Rutuja R Shah, Poonam J Patil, Pratibha R Adnaik, Rahul S Adnaik. Biochemical profiling of Antifungal soap activity of betel leaf (Piper betle L.) extract and Garlic oil by In vitro method. Asian J. Pharm. Res. 2020; 10(4):260-262. doi: 10.5958/2231-5691.2020.00045.3

Cite(Electronic):
Rutuja R Shah, Poonam J Patil, Pratibha R Adnaik, Rahul S Adnaik. Biochemical profiling of Antifungal soap activity of betel leaf (Piper betle L.) extract and Garlic oil by In vitro method. Asian J. Pharm. Res. 2020; 10(4):260-262. doi: 10.5958/2231-5691.2020.00045.3   Available on: https://asianjpr.com/AbstractView.aspx?PID=2020-10-4-3


REFERENCES:
1.    Yoshida, S.; Kasuga, S.; Hayashi, N.; Ushiroguchi, T.; Matsuura, H.; Nakagawa, Antifungal activity of ajoene derived from garlic. Appl. Environ. Microbiol.1987,53, 615–617.
2.     Rutuja R. Shah, Rohan R. Vakhariya. Formulation and Evaluation of Antifungal Soap of Garlic Oil. Asian J. Pharm. Res. 2020; 10(1):13-16.
3.    Sarika Pawar, Vidya Kalyankar, Bela Dhamangaonkar, Sharada Dagade, Shobha Waghmode and Abhishek Cukkemane, Biochemical profiling of antifungal activity of betel leaf (Piper betle L.) extract and its significance in traditional medicine, Adv Res Biotech 2(1): 4.
4.    A Touré1, C Bahi1, I Bagré1, JD N’Guessan1, AJ Djaman and A Coulibaly1. In vitro Antifungal Activity of the Soap Formulation of the Hexane Leaf Extract of Morinda morindoides (Morinda; Rubiaceae) Tropical Journal of Pharmaceutical Research June 2010; 9 (3): 237-241
5.    Namo Jeremiah Akuaden, I. Y. Chindo, Joel Ogboji, Formulation, Physicochemical and Antifungi Evaluation of Herbal Soaps of AzadiractaIndica and ZiziphusMauritiana, IOSR Journal of Applied Chemistry (12) 8 August. 2019, 26-34.
6.    Shao, P.L.; Huang, L.M.; Hsueh, P.R. Recent advances and challenges in the treatment of invasive fungal infections. Int. J. Antimicrob. Agents 2007

Recomonded Articles:

Author(s): S.K. Purohit, R. Solanki, V. Mathur, M. Mathur

DOI:         Access: Open Access Read More

Author(s): Ganesh Akula, Rangu Nirmala, CH. Shanthipriya, S. Rohini Reddy, A. Jaswanth

DOI: 10.5958/2231-5691.2017.00010.7         Access: Open Access Read More

Author(s): Eswaraiah S., Swetha K., Lohita M., P. Jaya Preethi, B. Priyanka, Kiran Kumar Reddy

DOI:         Access: Open Access Read More

Author(s): S. A. Mohite, R. R. Shah, N. R. Patel

DOI: 10.5958/2231-5691.2018.00004.7         Access: Open Access Read More

Author(s): P. Jaya Preethi, K. Bindu Sree, K. Pavan Kumar, R. Rajavelu , T. Sivakumar

DOI:         Access: Open Access Read More

Author(s): Mariam K. Abdrabaa, May T. Flayyih

DOI: 10.5958/2231-5691.2018.00038.2         Access: Open Access Read More

Author(s): Rinku K. Patel, Harsha U. Patel , C. N. Patel

DOI:         Access: Open Access Read More

Author(s): Nachiket S. Dighe, Pankaj Shinde, Harshali Anap, Sanjay Bhawar, Deepak S. Musmade

DOI:         Access: Open Access Read More

Author(s): Rutuja R. Shah, Rohan R. Vakhariya

DOI: 10.5958/2231-5691.2020.00003.9         Access: Open Access Read More

Author(s): Nilima Thombre, Madhura Thete, Pranali Shimpi

DOI: 10.5958/2231-5691.2020.00055.6         Access: Open Access Read More

Author(s): Rutuja R Shah, Poonam J Patil, Pratibha R Adnaik, Rahul S Adnaik

DOI: 10.5958/2231-5691.2020.00045.3         Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5691 


Recent Articles




Tags