Author(s):
Arindam Chatterjee, Amrita Pandey, Mayank Bansal, Sunil Sain, Ashutosh Sharma
Email(s):
amritapharma3@gmail.com
DOI:
10.52711/2231-5691.2024.00044
Address:
Arindam Chatterjee1, Amrita Pandey2*, Mayank Bansal2, Sunil Sain2, Ashutosh Sharma2
1Institute of Pharmacy, Assam Don Bosco University, Tepesia, Assam, India.
2Department of Pharmaceutics, Jaipur College of Pharmacy, Sitapura, Jaipur. Rajasthan, India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 3,
Year - 2024
ABSTRACT:
Microparticles, microspheres, and microcapsules are common multiparticulate drug delivery systems with technological and medical benefits. Microparticles are employed extensively these days. In order to improve efficacy, tolerance, and patient compliance, microparticles are used as multi-unit drug delivery systems with clearly defined physiological and pharmacokinetic benefits. The size of their particles varies from 0.1 to 1000 µm. A range of polymers have been employed in the synthesis of microparticles for drug delivery research in an effort to boost therapeutic efficacy while reducing negative effects. These days, glass, ceramic, and polymers are used to create microparticles. This method is used to deliver medications to particular regions. Microparticles are also used for regulated, prolonged, and long-term release. to treat a variety of illnesses, including inflammation, cancer, heart disease, ocular disorders, and psychotic disorders. This review covers the pros, cons, type of microparticles, preparation method, evaluation of microparticles and applications.
Cite this article:
Arindam Chatterjee, Amrita Pandey, Mayank Bansal, Sunil Sain, Ashutosh Sharma. A Panoramic Review on Microparticles. Asian Journal of Pharmaceutical Research. 2024; 14(3):285-8. doi: 10.52711/2231-5691.2024.00044
Cite(Electronic):
Arindam Chatterjee, Amrita Pandey, Mayank Bansal, Sunil Sain, Ashutosh Sharma. A Panoramic Review on Microparticles. Asian Journal of Pharmaceutical Research. 2024; 14(3):285-8. doi: 10.52711/2231-5691.2024.00044 Available on: https://asianjpr.com/AbstractView.aspx?PID=2024-14-3-13
REFERENCES:
1. M K Das, A B Ahmed, and D Saha. Microsphere a drug delivery system: A review. Int J Curr Pharm Res. 2019; 11(4): 34–41.
2. P Parida, S C Mishra, S Sahoo, A Behera, and B P Nayak. Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine. Journal of Pharmaceutical Analysis, 2016; 6(5): 341–344.
3. Dhadde Gurunath S, Mali Hanmant S, Raut Indrayani D, Nitalikar Manoj M, Bhutkar Mangesh M. A Review on Microsphere: Types, Method of Preparation, Characterization and Application. Asian Journal of Pharmacy and Technology. 2021; 11(2): 149-55. Doi: 10.52711/2231-5713.2021.00025
4. Nikita Agnihotri, Chirag Goda, Mishra, Microencapsulation A novel approach in drug delivery-Review May 2012.
5. Leon L, Herbert AL and Joseph LK (1990). The Theory and Practice of Industrial Pharmacy, 3rd edition (Varghese Publishing House) 412, 428.
6. James Swar Brick, James Boylan E, Mercel Dekkar. Microencapsulation technology and applications. Encyclopedia of Pharmaceutical Technology. 1988; 10: 245-286
7. Kinam Park, Yoon Yeo. Microencapsulation technology Encyclopedia of Pharmaceutical Technology GEPT. 2002; 6(2): 67-85.
8. Kriti Ranjan Parida, Sanjay Kumar Panda, Palaniyandi Ravanan, Harekrishna Roy, Madhumati Maniokam, Priti Talwar. Micro particles based drug delivery system: preparation and applications on cancer therapeutics. International Archive of Applied Science and Technology.
9. Kadam NR, Suvarna V. Asian Journal of Biomedical and Pharmaceutical Sciences. 2015; 5(47): 13-19.
10. Shoba Rani R, Hiremath. Text Book of Industrial Pharmacy 1st edition Black Swan Publishers Ltd, Chennai, 2008, 117-128.
11. Nixon J R. In vitro and in vivo release of microencapsulated chlorothiazide, Proc. 4th Int. Symp. Microencap., Miami, FL, 1981; 26–28
12. Ozer A Y and Hincal A. A Studies on the masking of unpleasant taste of beclamide microencapsulation and tableting. J. Microencap. 1990; 7: 327–339.
13. Tirkkonen S and Paronen P. Release of indomethacin tabletted ethylcellulose microcapsules. Int. J. Pharm. 1993; 92: 55– 62.
14. Salib N N, El-Menshawy M E and Ismail A A. Ethyl cellulose as a potential sustained release coating for oral pharmaceuticals. Pharmazie. 1976; 31: 721–723.
15. Tirkkonen S and Paronen P. Release of indomethacin tabletted ethylcellulose microcapsules. Int. J. Pharm. 1993; 92: 55– 62.
16. Lu M F, Borodkin S, Woodward L and Vadnere M. Polymer carrier system for taste masking of macrolide antibiotics. Pharm. Res. 1991; 8: 706–712.
17. Tunçel T, Bergisadi N, Akin L, Otuk G and Kuscu I. In vitro and in vivo studies on microcapsules and tabletted microcapsules of cephradine. Pharmacie. 1996; 51: 168–171.
18. Goto S, Komatsu M, Tagawa K and Kawata M. Preparation and evaluation of gelatine microcapsules of sulfonamides. Chem. Pharm. Bull. 1983; 31: 256–261
19. Green, B. K., US Patent 2,800,458, July 23, 1957.
20. N. V. Satheesh Madhav, Shivani Kala. Review on microparticulate drug delivery system. International Journal of Pharma Tech Research. 2011; 3.