Author(s): Manisha Rokade, Pradnya Khandagale


DOI: 10.5958/2231-5691.2020.00042.8   

Address: Manisha Rokade, Pradnya Khandagale
KCT’S R.G. Sapkal Institute of Pharmacy, Anjanei Nashik.
*Corresponding Author

Published In:   Volume - 10,      Issue - 3,     Year - 2020

In December 2019, several patients from Wuhan, China were admitted to hospitals with symptoms of pneumonia. As the number of patients presenting with similar symptoms started to rise, the causative agent was eventually isolated from samples. It was initially called the 2019 novel coronavirus (2019-nCoV) and has been recently relabelled as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); the disease it causes has been named coronavirus disease 2019 (COVID-19). Over the next few weeks, the virus spread from Wuhan to affect different provinces in China and, after a few months, it is now present in 109 countries. As of March 10, 2020, there have been 113,702 confirmed cases globally, and 4,012 deaths have been registered. The World Health Organization (WHO) called COVID-19 a pandemic on March 11, 2020. There are multiple drug trials going on with some positive results. However, since no vaccine is available, the best way to combat the virus is by preventive methods.

Cite this article:
Manisha Rokade, Pradnya Khandagale. Coronavirus Disease: A Review of a New Threat to Public Health. Asian J. Pharm. Res. 2020; 10(3):241-244. doi: 10.5958/2231-5691.2020.00042.8

Manisha Rokade, Pradnya Khandagale. Coronavirus Disease: A Review of a New Threat to Public Health. Asian J. Pharm. Res. 2020; 10(3):241-244. doi: 10.5958/2231-5691.2020.00042.8   Available on:

1. Centers for Disease Control and Prevention: coronavirus disease 2019 (COVID-19) - situation summary. (2020). Accessed: March 11, 2020: summary.html.
2. Centers for Disease Control and Prevention: human coronavirus types. (2020). Accessed: March 11, 2020: coronavirus/types.html.
3. WHO: coronavirus disease (COVID-2019) situation reports. (2020). Accessed: March 11, 2020: emergencies/diseases/novel-coronavirus-2019/situation-reports.
4. Chen N, Zhou M, Dong X, et al.: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020, 395:507-13. 10.1016/S0140-6736(20)30211-7
5. Letko M, Marzi A, Munster V: Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol. 2020, Accessed: March 15, 2020: 10.1038/s41564-020-0688-y
6. Gralinski LE, Menachery VD: Return of the Coronavirus: 2019-nCoV. Viruses. 2020, 12: E135. Accessed: March 11, 2020: 10.3390/v12020135
7. Lu R, Zhao X, Li J, et al.: Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020, 395:565-74. 10.1016/S0140-6736(20)30251-8
8. Zhou P, Yang XL, Wang XG, et al.: A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020, 579:270-3. 10.1038/s41586-020-2012-7
9. Evidence of recombination in coronaviruses implicating pangolin origins of nCoV-2019. (2020). Accessed: March 11, 2020:
10. Peng X, Xu X, Li Y, Cheng L, Zhou X, Ren B: Transmission routes of 2019-nCoV and controls in dental practice. Int J Oral Sci. 2020, 12:9. 10.1038/s41368-020-0075-9
11. Identification of a pangolin niche for a 2019-nCoV-like coronavirus through an extensive meta-metagenomic search. (2020). Accessed: March 11, 2020: content/10.1101/2020.02.08.939660v2.
12. Centers for Disease Control and Prevention: how COVID-19 spreads. (2020). Accessed: March 11, 2020: coronavirus/2019-ncov/about/transmission.html.
13. Guan WJ, Ni ZY, Hu Y, et al.: Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020, 10.1056/NEJMoa2002032
14. Wu Z, McGoogan JM: Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020, 10.1001/jama.2020.2648
15. Cai J, Xu J, Lin D, et al.: A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020, 10.1093/cid/ciaa198
16. Wei M, Yuan J, Liu Y, Fu T, Yu X, Zhang ZJ: Novel coronavirus infection in hospitalized infants under 1 year of age in China. JAMA. 2020, 10.1001/jama.2020.2131
17. Centers for Disease Control and Prevention: persons evaluated for 2019 novel coronavirus — United States, January 2020. (2020). Accessed: March 11, 2020: 69/wr/mm6906e1.htm?s_cid=mm6906e1_x.
18. Coronavirus disease 2019 (COVID-19). (2020). Accessed: March 11, 2020:
19. Lim J, Jeon S, Shin HY, et al.: Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR. J Korean Med Sci. 2020, 35:e79. 10.3346/jkms.2020.35.e79
20. Wang Z, Chen X, Lu Y, Chen F, Zhang W: Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment. Biosci Trends. 2020, 10.5582/bst.2020.01030
21. Young BE, Ong SWX, Kalimuddin S, et al.: Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore. JAMA. 2020, 10.1001/jama.2020.3204
22. Lu H: Drug treatment options for the 2019-new coronavirus (2019-nCoV). Biosci Trends. 2020, 10.5582/bst.2020.01020
23. National Institutes of Health: novel coronavirus structure reveals targets for vaccines and treatments. (2020). Accessed: March 11, 2020: novel-coronavirus-structure-reveals-targets-vaccines-treatments.
24.   Centers for Disease Control and Prevention: coronavirus disease 2019 (COVID-19) - how to protect yourself. (2020). Accessed: March 11, 2020: about/prevention.html.

Recomonded Articles:

Author(s): Manisha Rokade, Pradnya Khandagale

DOI: 10.5958/2231-5691.2020.00042.8         Access: Open Access Read More

Author(s): Dhanashri Aware, Sachin Rohane

DOI: 10.52711/2231-5691.2021.00037         Access: Open Access Read More

Author(s): Ritika Gupta

DOI: 10.5958/2231-5691.2020.00056.8         Access: Open Access Read More

Author(s): Subhashis Debnath, Runa Chakravorty, Donita Devi

DOI: 10.52711/2231-5691.2021.00022         Access: Open Access Read More

Author(s): Kandra Naga Vishnu, Praveen Kumar Uppala, Yakaiah Vangoori, Siva Naga Koteswara Rao Gudhanti

DOI: 10.52711/2231-5691.2021.00042         Access: Open Access Read More

Author(s): Swati G. Talele, Eknath D. Ahire, Khemchand R. Surana, Vijayraj N. Sonawane, Gokul S. Talele

DOI: 10.52711/2231-5691.2022.00008         Access: Closed Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5691 

Recent Articles