REFERENCES:
1. Al-Waili N, Al-Waili H, Al-Waili T, and Salom K. Natural antioxidants in the treatment and prevention of diabetic nephropathy; a potential approach that warrants clinical trials. REDOX REPORT. 2017, 22 (3): 99–118.
2. Muller-Deile J, Schiffer M. The podocyte power-plant disaster and its contribution to glomerulopathy. Frontier in endocrinology. 2014, 5 (209): 1- 6.
3. Vega-Warner V, Ransom RF, Vincent AM, et al. Induction of antioxidant enzymes in murine podocytes precedes injury by puromycin aminonucleoside. Kidney Int. 2004, 66:1881-1889.
4. Shankland SJ. The Podocyte’s Response to Injury: Role in Proteinuria and Glomerulus. Kidney Int. 2006, 09:2131 – 2147.
5. Kriz W, LeHir M. Pathways to nephron loss starting from glomerular diseases-insights from animal models. Kidney Int. 2005, 67: 404-419.
6. Tavafi M. Diabetic nephropathy and antioxidants. J Nephropathology. 2013, 2:20-27.
7. Liu P, Feng Y, Wang Y, Zhou Y, and Zhao L. Protective effect of vitamin E against acute kidney injury. Biomed. Mater. Eng. 2015, 26: S2133–S2144.
8. Serbinova E, Kagan V, Han D, Packer L. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic Biol Med. 1991, 10(5):263-75.
9. Koya D, Hayashi K, Kitada M, Kashiwagi A, Kikkawa R, and Haneda M. Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats. J. Am. Soc. Nephrol. 2003, 14 (8 Suppl. 3): S250–S253.
10. Haidara MA, Mikhailidis DP, Rateb MA., et al. Evaluation of the effect of oxidative stress and vitamin E supplementation on renal function in rats with streptozotocin induced Type 1 diabetes. J. Diabetes Complications. 2009, 23: 130–136.
11. Hayashi D, Yagi K, Song C et al. Diacylglycerol kinase alpha is involved in the vitamin E-induced amelioration of diabetic nephropathy in mice. Sci. Rep. 2017,7:2597.
12. Jeanette S, Alex K, and Adviye E. Oxidative stress and the use of antioxidants in diabetes. Cardiovasc Diabetol. 2005, 4:5–9.
13. Tursun A, Astumi N, Hiroyuki M, et al. A natural scavenger of peroxynitrites, protects against impairment of memory induced by Ab25–35. Behav Brain Res.2007;180:139–145.
14. Mushtaq N, Schmatz R, Ahmed M, et al. Protective effect of rosmarinic acid against oxidative stress biomarkers in liver and kidney of strepotozotocin-induced diabetic rats. J Physiol Biochem.2015, 71(4):743–751.
15. Jiang WL, Xu Y, Zhang SP, Hou J, Zhu HB. Effect of Rosmarinic Acid on Experimental Diabetic Nephropathy. Basic & clinical pharmacology & toxicology. 2012, 110 (4): 390–395
16. Moskaug JO, Carlsen H, Myhrstad MC, Blomhoff R. Polyphenols and glutathione synthesis regulation. Am J Clin Nutr. 2005, 81(1):277S–283S.
17. Samsu N, Soeharto S, Rifai M, et al. Rosmarinic acid monotherapy is better than the combination of rosmarinic acid and telmisartan in preventing podocyte detachment and inhibiting the progression of diabetic nephropathy in rats. Biologics: Targets and Therapy 2019:13 179–190
18. Furman BL. Streptozotocin-induced diabetic models in mice and rats. Current protocol in pharmacology. 2015, 7(1): 5.47.1 – 5.47.20.
19. Rangan G and Tesch GH. Quantification of renal pathology by image analysis (Methods in Renal Research). NEPHROLOGY. 2007, 12: 553–558.
20. Zhao Y, Zhang W, Jia Q, et al. High Dose Vitamin E Attenuates Diabetic Nephropathy via Alleviation of Autophagic Stress. Front. Physiol. 2019, 9:1939.
21. Hirnerová E, Krahulec B, Strbová L, et al. Effect of vitamin E therapy on progression of diabetic nephropathy. Vnitr Lek. 2003, 49(7):529–534.
22. Hirnerova E, Krahulec B, Strbova L, et al. Effect of vitamin E supplementation on microalbuminuria, lipid peroxidation and blood prostaglandins in diabetic patients. Bratisl Lek Listy. 2004, 105:408–413.
23. Farvid MS, Jalali M, Siassi F, Hosseini M. Comparison of the effects of vitamins and/or mineral supplementation on glomerular and tubular dysfunction in type2 diabetes. Diabetes care. 2005;28(10):2458–2464.
24. Gaede P, Poulsen HE, Parving HH, Pedersen O. Double-blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type2 diabetic patients. Diabetic medicine: a journal of the British Diabetic Association. 2001, 18(9):756–760.
25. Reddy GR, Kotlyarevska K, Ransom RF, Menon RK. The podocyte and diabetes mellitus: is the podocyte the key to the origins of diabetic nephropathy? Curr Opin Nephrol Hypertens. 2008, 17(1):32-36.
26. Greiber S, Muller B, Daemisch P, Pavenstadt H. Reactive oxygen species alter gene expression in podocytes: Induction of granulocyte macrophage‐colony‐stimulating factor. J. Am. Soc. Nephrol. 2002, 13: 86– 95.
27. Nam J, Cho M, Lee G. The activation of NF-κB and AP-1 in peripheral blood mononuclear cells isolated from patients with diabetic nephropathy. Diabetes Res Clin Prac. 2008, 81:25–32.
28. Baynes W and Thorpe S. The role of oxidative stress in diabetic complications. Cur Opininion Endocrinol Diabetes. 1996, 3:277 – 284.
29. Hussain S, Romio L, Saleem M et al. Nephrin Deficiency Activates NF-κB and Promotes Glomerular Injury. J Am Soc Nephrol. 2009, 20 (8): 1733–1743.
30. Kumar PA, Welsh GI, Raghu G et al. Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus. Arch Biochem Biophys. 2006, 590: 10–19.
31. Otero P, Bonet B, Herrera E, Rabano A. Development of atherosclerosis in the diabetic BALB/c mice prevention with vitamin E administration. Atheroscler. 2005, 182:259–65.
32. Shirpoor A, Iikhanizadeh B, Saadatian R, et al. Effect of Vitamin E on diabetes-induced changes in small intestine and plasma antioxidant capacity in rats. J Physiol Biochem 2006, 62: 171-177.
33. Jayanthy G and Subramanian S. Rosmarinic acid, a polyphenol, ameliorates hyperglycemia by regulating the key enzymes of carbohydrate metabolism in high fat diet – STZ induced experimental diabetes mellitus. Biomedicine & Preventive Nutrition, 2014:431-437.
34. Li B, Cui W, Tan Y, et al. Zinc is essential for the transcription function of Nrf2 in human renal tubule cells in vitro and mouse kidney in vivo under the diabetic condition. J Cell Mol Med. 2014, 18 (5):895–906.
35. Comper WD, Osicka TM, and Jerums G. “High prevalence of immuno-unreactive intact albumin in urine of diabetic patients,” AJKD, 2003, 41 (1): 336–342.
36. Rao X, Wan M, Qiu Q, and Jiang C. “Role of cystatin C in renal damage and the optimum cut-off point of renal damage among patients with type 2 diabetes mellitus,” Experimental and Therapeutic Medicine, 2014: 8 (3): 887–892.
37. Schuck O, Teplan V, Sibova J, Stollova M. Predicting the glomerular filtration rate from serum creatinine, serum cystatin C and the Cockcroft and Gault formula with regard to drug dosage adjustment. Int J Clin Pharmacol Ther. 2004; 42:93-7