Osteoarthritis: Pathophysiology and Current Treatment Modalities

Kanchan R Pagar; Sarika V Khandbahale; Poonam M Kasar

doi:10.5958/2231-5691.2019.00046.7

Asian Journal of Pharmaceutical Research

ISSN

2231-5691 (Online)
2231-5683 (Print)

Submit Article

Osteoarthritis: Pathophysiology and Current Treatment Modalities

Author(s): Kanchan R Pagar, Sarika V Khandbahale, Poonam M Kasar

Email(s): sarikakhandbahale76@gmail.com

DOI: 10.5958/2231-5691.2019.00046.7

Address: Kanchan R Pagar, Sarika V Khandbahale, Poonam M Kasar
R G Sapkal Institute of Pharmacy, Anjaneri, Nashik
*Corresponding Author

Published In: Volume - 9, Issue - 4, Year - 2019

View HTML

View PDF

ABSTRACT:
Osteoarthritis (OA) is accepted as a major public health problem. It is one of the major causes of impaired function that reduces quality of life (QOL) worldwide. OA is a very common disorder affecting the joint cartilage. As there is no cure for OA, treatments currently focus on management of symptoms. Pain relief, improved joint function, and joint stability are the main goals of therapy. The muscle weakness and muscle atrophy contribute to the disease process. So, rehabilitation and physiotherapy were often prescribed with the intention to alleviate pain and increase mobility. However, as exercise has to be performed on a regular basis in order to counteract muscle atrophy, continuous exercise programs is recommended in people with degenerative joint disease. Therapeutic exercise regimes either focus on muscle strengthening and stretching exercises or on aerobic activity which can be land or water based. This article presents on overview of the current knowledge on OA and focuses on biomechanics, etiology, diagnosis and treatment strategies, conservative treatment including the physical therapy management are discussed. This information should assist health care practioners who treat patients with this disorder.

Keywords:

Cite this article:
Kanchan R Pagar, Sarika V Khandbahale, Poonam M Kasar. Osteoarthritis: Pathophysiology and Current Treatment Modalities. Asian J. Pharm. Res. 2019; 9(4):289-298. doi: 10.5958/2231-5691.2019.00046.7

Cite(Electronic):
Kanchan R Pagar, Sarika V Khandbahale, Poonam M Kasar. Osteoarthritis: Pathophysiology and Current Treatment Modalities. Asian J. Pharm. Res. 2019; 9(4):289-298. doi: 10.5958/2231-5691.2019.00046.7 Available on: https://asianjpr.com/AbstractView.aspx?PID=2019-9-4-10

Recomonded Articles:

Screening Models for CNS Stimulant Drugs: A Review

Author(s): Jaya Preethi P, Padmini K, Srikanth J, Lohita M, Swetha K

DOI: Access: Open Access Read More

Traditional Herbs to treat Acne Vulgaris

Author(s): Sonali Syal, Vinay Pandit, M. S Ashawat

DOI: 10.5958/2231-5691.2020.00034.9 Access: Open Access Read More

Pharmacological and Phytochemical Evidences for the Plants of Wedelia Genus– A Review

Author(s): AK Meena, MM Rao, RP Meena, P Panda, Renu

DOI: Access: Open Access Read More

Sublingual Tablets - An Updated Review

Author(s): Ashok Thulluru, Nawaz Mahammed, C. Madhavi, K. Nandini, S. Sirisha, D. Spandana

DOI: 10.5958/2231-5691.2019.00016.9 Access: Open Access Read More

Self-nano Emulsifying Drug Delivery System (SNEDDS): Future Aspects

Author(s): Hiral A. Makadia, Ami Y. Bhatt, Ramesh B. Parmar, Ms. Jalpa S. Paun, H.M. Tank

DOI: Access: Open Access Read More

A Review on Microsphere and it’s Application

Author(s): Kaustubh V. Gavali, Manohar D. Kengar, Kiran V. Chavan, Vaishnavi P. Anekar, Naziya I. Khan

DOI: 10.5958/2231-5691.2019.00020.0 Access: Open Access Read More

Review on Solubility Enhancement Techniques

Author(s): B.A. Bhairav, J.K. Bachhav, R.B. Saudagar

DOI: 10.5958/2231-5691.2016.00025.3 Access: Open Access Read More

The Review on The Nasal Drug Delivery

Author(s): Prajapati M., Mandloi R., Pillai S, Birla N.

DOI: 10.5958/2231-5691.2020.00021.0 Access: Open Access Read More

Formulation and Evaluation of Antifungal Soap of Garlic Oil

Author(s): Rutuja R. Shah, Rohan R. Vakhariya

DOI: 10.5958/2231-5691.2020.00003.9 Access: Open Access Read More

Study of Different Granulation Processes during Formulation Development, Evaluation, Characterization of Granules and Capsule Formulations

Author(s): Hemant Patel

DOI: Access: Open Access Read More

A detailed investigation of phytochemical, biological and commercial utilization of horse tail tree Casuarina equisetifolia

Author(s): Vani Mamillapalli, Latha Sri Kondaveeti, Ratna Harika Chapala, Tejaswi Komal Sai. Sareddu, Santhi Pattipati, Padmalatha Khantamneni

DOI: 10.52711/2231-5691.2022.00014 Access: Open Access Read More

Application of Panchakarma to Prevent Disease

Author(s): KVM. Krishna, Kshema Hasanthi, Sanjana Joshi, Ramesh Alluri

DOI: Access: Open Access Read More

Curry Leaves – A Medicinal Herb

Author(s): Sinha Parul , Akhtar Javed , Batra Neha , Jain Honey , Bhardwaj Anuj

DOI: Access: Open Access Read More

A Review- Nanosuspension Technology in Drug Delivery System

Author(s): Sarika V. Khandbahale

DOI: 10.5958/2231-5691.2019.00021.2 Access: Open Access Read More

A Brief Review on Genotoxic impurities in Pharmaceuticals

Author(s): Ashok B. Patel, Ashish H. Asnani, Amitkumar J. Vyas, Nilesh K. Patel, Ajay I. Patel, Arvind N. Lumbhani

DOI: 10.52711/2231-5691.2021.00034 Access: Open Access Read More

Design, Development and Evaluation of Enteric Coated Tablets of Glimepiride

Author(s): Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum

DOI: 10.5958/2231-5691.2017.00024.7 Access: Open Access Read More

A Study on Formulation and Evaluation of Herbal Hand Sanitizer and Herbal Handwash

Author(s): Priyanka Kusarkar, Mayuri Kupkar, Trupti Dudhgaonkar

DOI: 10.52711/2231-5691.2022.00032 Access: Open Access Read More

A Review on New Herbal Remedies for treatment of Mouth Ulcer

Author(s): Rina G. Maskare, Ayush P. Agrawal, Mayuri S. Pal, Jidnyasa R. Yerne, Megham Chaudhri, Anup R. Bawankar, Gaytri B. Sonkusre

DOI: 10.52711/2231-5691.2022.00025 Access: Open Access Read More

Emulgel: A Review

Author(s): Sahil Hasan, Saloni Bhandari, Anshu Sharma, Poonam Garg

DOI: 10.52711/2231-5691.2021.00047 Access: Open Access Read More

Ethno Pharmacological Uses of Artocarpus altilis– A Review

Author(s): Vidya Raju*, Jasmine Joy Bell, Merlin. N. J, Shaiju S Dharan

DOI: 10.5958/2231-5691.2017.00037.5 Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available
DOI: 10.5958/2231–5691