Earle Radha Rani, M. Ramadevi, Ayalasomayajula Lakshmi Usha
Earle Radha Rani*, M. Ramadevi, Ayalasomayajula Lakshmi Usha
Department of Pharmaceutics, Maharajah’s College of Pharmacy, Vizianagaram, A.P., India.
Volume - 11,
Issue - 1,
Year - 2021
Hydrogels are a group of polymeric materials, usually hydrophilic and are capable of holding large amounts of water in their three-dimensional networks. They became very popular in the recent times because of their unique properties such as high water content, softness, flexibility and biocompatibility. Hydrogels can be prepared by cross linking of natural and synthetic hydrophilic polymers physically or chemically. They have a vast application in biomedical area as they resemble the living tissue. Currently, hydrogels are used in the manufacture of contact lenses, hygiene products, tissue engineering scaffolds, drug delivery systems and wound dressings. This review provides information regarding the characteristics, biomedical applications and perspective on further potential developments of hydrogels.
Cite this article:
Earle Radha Rani, M. Ramadevi, Ayalasomayajula Lakshmi Usha. An Overview on Hydrophilic three-Dimensional Networks: Hydrogels.Asian J. Pharm. Res. 2021; 11(1):23-28. doi: 10.5958/2231-5691.2021.00006.X
1. Peppas NA, Bures P, Leobandung W, Ichikaw H. Eur J Pharm Biopharm 2000; 50:27-46.
2. Jayesh SG, Yogita VD. Comprehensive review on hydrogels. Asian. J. Pharm. Tech. 2018; 8(3): 172-181.
3. Nandhakumar L, Dharmamoorthy G, Chandrasekaran S. Hydrogels: A multifaceted contemporary approaches and advancements. Research J.Pharm. and Tech. 2011; 4 (11); 1658-1662.
4. Hoare TR, Kohane DS. Hydrogels in drug delivery: progress and challenges. Polymers 2007; 49 (8): 1993-2007.
5. Misra GP, Gardner TW, Lowe TL. Hydrogels for ocular posterior segment drug delivery. AAPS Advances in the Pharmaceutical Sciences Series 2011; 291-304.
6. Reena B, Mitra UK. Synthesis and characterization of polyacrylamide hydrogels. Asian J. Research Chem. 2014; 7 (3): 345-348.
7. Reena B. Electrochemical synthesis of polyacrylamide hydrogels- metalnanoparticles composites. Asian J. Research Chem 2014; 7 (6); 593-595.
8. Lin-Gibson S, Bencherif S, Cooper JA, Wetzel SJ, Antonucci JM, Vogel BM et al. Biomacromolecules 2004; 5: 1280-1287.9.
9. Osuagwu UL, Ogbuehi KC. Contact Lens Anterior Eye 2014; 37:136-143.
10. Jacob JT. Eye Contact Lens 2013; 39: 13-19.
11. Singh D, Daharwal SJ, Rawat M. Hydrogels- a potent carter in wound healing. Research J.Pharm. and Tech. 2008; 1(1): 6-13.
12. Buchlholz FL, Peppas NA. Superabsorbent polymers science and technology. American Chemical Society Washington 1994; 7: 88-98.
13. A. Flores. Kingsley Wound Essentials 2007; 2: 182-183.
14. Tan H, Marra KG. Injectable biodegradable hydrogels for tissue engineering applications 3(3); 1746–1767.
15. Sneha VS, Shirish VS, Kisan RJ, Vilasrao JK. Hydrogel as drug delivery system. Research J.Pharm. and Tech 2012; 5 (5); 561-569.
16. Bierbrauer F. Hydrogel drug delivery: diffusion models. Internal Report. 1-31.
17. Azagury A. Adv. Drug Deliv. Rev. 2014; 72: 127-143.
18. Bouten PJM, Zonjee M, Bender J, Yauw STK, Van GH, Van JCM et al. Prog Polym Sci 2014; 39: 1375-1405.
19. Schlegel PN, Kuzma P, Frick J, Farkas A, Gomahr A, Spitz I et al. Urology 2001; 58: 578-582.
20. Battaglia et al. Ocular delivery of solid lipid nanoparticles lipid nanocarriers for drug targeting 2018; 269-312.
21. Benson HA. Transdermal drug delivery: penetration enhancement techniques. Current Drug Delivery 2005; 2 (1): 23-33.
22. Efron N. Trends in US contact lens prescribing. Optom. Vis. Sci 2015; 92 (7): 758-767.
23. Martin P. Wound healing–aiming for perfect skin regeneration. Science 1997; 276 (5309): 75-81.
24. Nicolson PC, Vogt J. Soft contact lens polymers: Biomaterials 2001; 22 (24); 3273-3281.
25. Venkata RRK, Nagabhushanam MV, Ravindra NE. Swellable hydrogels and cross linking agents- their role in drug delivery system. Research J. Pharm. and Tech 2017; 10 (3): 937-943.
26. Homendra KS, Kamdev S, Raju P, Hulash S, Deepika S, Gulshan S et al. An overview on the established pharmaceutical aspects associated with the development of hydrogels. Research J. Pharm. and Tech 2017; 10 (3): 944-953.
27. Ravindra NE, Venkata RRK, Swetha N. Super porous hydrogels. Research J. Pharm and Tech 2019; 12 (1): 434-442.