Author(s): Tejshri Tambe, Mayur Bhosale, Pankaj Sonawane, Sonali Shinde


DOI: 10.52711/2231-5691.2022.00039   

Address: Tejshri Tambe*, Mayur Bhosale, Pankaj Sonawane, Sonali Shinde
Pravara Rural College of Pharmacy, Pravaranagar, A/P- Loni - 413736, Tal - Rahata, Dist - Ahmednagar.
*Corresponding Author

Published In:   Volume - 12,      Issue - 3,     Year - 2022

Spirulina stands out as a sustainable bioactive microalga with health­ promoting parcels, and an important active element of natural cosmetics products. Presently, Spirulina has been incorporated in topical skin­ care phrasings, similar as a moisturizing, antiwrinkles, antiaging and antiacne agent. Likewise, this microalga is used by ornamental inventors to promote healthy sunscreen protection, to treat skin achromatism conditions and to heal injuries. Utmost of marketablecosmetics claim an outsized range of Spirulina parcels, including antioxidant, revitalizing, remineralizing, moisturizing, guarding alongside sanctification and shining action, both for hair and for skin. In this review, recent ornamental operations of Spirulina are revised, by pressing its capability in perfecting skin appearance and health. Also, the analysis of the Spirulina ornamental standardis mooted. Looking at the current emergence of the beauty assiduity, numerous Spirulina extracts anddry cream/ flakes, both the starting element and final Spirulina­ rested ornamental products, areavailable on the request. In this artificial field, Spirulina — substantially Spirulina platensis and Spirulinamaxes — is used either as a cream, like in the case of cheaper products, or as a phycocyanin­richblue Extract, particularly in the luxury request.

Cite this article:
Tejshri Tambe, Mayur Bhosale, Pankaj Sonawane, Sonali Shinde. A Review on: Therapeutic Activities of Spirulinaon skin. Asian Journal of Pharmaceutical Research. 2022; 12(3):235-0. doi: 10.52711/2231-5691.2022.00039

Tejshri Tambe, Mayur Bhosale, Pankaj Sonawane, Sonali Shinde. A Review on: Therapeutic Activities of Spirulinaon skin. Asian Journal of Pharmaceutical Research. 2022; 12(3):235-0. doi: 10.52711/2231-5691.2022.00039   Available on:

1.    Miranda, M.; Cintra, R.; Barros, S.d.M.; Mancini-Filho, J. Antioxidant activity of the microalga Spirulina maxima. Braz. J. Med.Biol. Res. 1998, 31, 1075–1079.
2.    Khan, Z.; Bhadouria, P.; Bisen, P. Nutritional and therapeutic potential of Spirulina. Curr. Pharm. Biotechnol. 2005, 6, 373–379.
3.    Clément, G.; Giddey, C.; Menzi, R. Amino acid composition and nutritive value of the alga Spirulina maxima. J. Sci. Food Agric.1967, 18, 497–501.
4.    Tomaselli, L. Morphology, ultrastructure and taxonomy of Arthrospira (Spirulina) maxima and Arthrospira (Spirulina) platensis. In Spirulina Platensis (Arthrospira): Physiology, Cell-Biology and Biotechnology; Taylor and Francis: Abingdon, UK, 1997; pp. 1–16.
5.    Belay, A. Spirulina (Arthrospira): Production and quality assurance. In Spirulina in Human Nutrition and Health; CRC Press: Boca Raton, FL, USA, 2008; Volume 1.
6.    Babadzhanov, A.; Abdusamatova, N.; Yusupova, F.; Faizullaeva, N.; Mezhlumyan, L.; Malikova, M.K. Chemical Composition of Spirulina platensis Cultivated in Uzbekistan. Chem. Nat. Compd. 2004, 40, 276–279.
7.    Vonshak, A. Spirulina Platensis Arthrospira: Physiology, Cell-Biology and Biotechnology; CRC Press: Boca Raton, FL, USA, 1997.
8.    Liestianty, D.; Rodianawati, I.; Arfah, R.A.; Assa, A. Nutritional analysis of spirulina sp to promote as superfood candidate.IOP Conf. Ser. Mater. Sci. Eng. 2019, 509, 012031. [CrossRef]
9.    Karkos, P.; Leong, S.; Karkos, C.; Sivaji, N.; Assimakopoulos, D. Spirulina in clinical practice: Evidence-based human applications. Evid. Based Complementary Altern. Med. 2011, 2011, 531053.
10.    Kennedy, D.O. B vitamins and the brain: Mechanisms, dose and efficacy—A review. Nutrients 2016, 8, 68.
11.    Wells, M.L.; Potin, P.; Craigie, J.S.; Raven, J.A.; Merchant, S.S.; Helliwell, K.E.; Smith, A.G.; Camire, M.E.; Brawley, S.H. Algae asnutritional and functional food sources: Revisiting our understanding. J. Appl. Phycol. 2017, 29, 949–982.
12.    Makkar, R.; Behl, T.; Bungau, S.; Zengin, G.; Mehta, V.; Kumar, A.; Uddin, M.; Ashraf, G.M.; Abdel-Daim, M.M.; Arora, S. Nutraceuticals in neurological disorders. Int. J. Mol. Sci. 2020, 21, 4424.
13.    Sorrenti, V.; Fortinguerra, S.; Caudullo, G.; Buriani, A. Deciphering the Role of Polyphenols in Sports Performance: From Nutritional Genomics to the Gut Microbiota toward PhytonutritionalEpigenomics. Nutrients 2020, 12, 1265.
14.    Sorrenti, V.; Ali, S.; Mancin, L.; Davinelli, S.; Paoli, A.; Scapagnini, G. Cocoa Polyphenols and Gut Microbiota Interplay: Bioavailability, Prebiotic Effect, and Impact on Human Health. Nutrients 2020, 12, 1908.
15.    Neyrinck, A.M.; Taminiau, B.; Walgrave, H.; Daube, G.; Cani, P.D.; Bindels, L.B.; Delzenne, N.M. Spirulina protects against h
16.    Hu, J.; Li, Y.; Pakpour, S.; Wang, S.; Pan, Z.; Liu, J.; Wei, Q.; She, J.; Cang, H.; Zhang, R.X. Dose effects of orally administered Spirulina suspension on colonic microbiota in healthy mice. Front. Cell. Infect. Microbiol. 2019, 9, 243.
17.    Bob Capelli, potential health benefit of spirullinamicroalge, lndependent Consultant.
18.    Pereira, L. Seaweeds as Source of Bioactive Substances and Skin Care Therapy—Cosmeceuticals, Algotheraphy, and Thalassotherapy. Cosmetics 2018, 5, 68.
19.    Villaret, A.; Ipinazar, C.; Satar, T.; Gravier, E.; Mias, C.; Questel, E.; Schmitt, A.; Samouillan, V.; Nadal, F.; Josse, G. Raman Characterization of Human Skin Aging. Ski. Res. Technol. 2019, 25, 270–276
20.    Mourelle, M.L.; Gómez, C.P.; Legido, J.L. The Potential Use of Marine Microalgae and Cyanobacteria in Cosmetics and Thalassotherapy. Cosmetics 2017, 4, 46.
21.    Lotan, A. Biologic Sunscreen Composition. World Patent No. WO 093388 A2, 12 July 2012.
22.    Souza, C.; Campos, P.M.B.G.M. Development and Photoprotective Effect of a Sunscreen Containing the Antioxidants Spirulina and Dimethylmethoxy Chromanol on Sun-Induced Skin Damage. Eur. J. Pharm. Sci. 2017, 104, 52–64.
23.    Souza, C.; de Freitas, L.A.P.; Maia Campos, P.M.B.G. Topical Formulation Containing Beeswax-Based Nanoparticles Improved In Vivo Skin Barrier Function. AAPS Pharm SciTech 2017, 18, 2505–2516.
24.    Delsin, S.; Mercurio, D.; Fossa, M.; Maia Campos, P. Clinical Efficacy of Dermocosmetic Formulations ContainingSpirulina Extract on Young and Mature Skin: Effects on the Skin Hydrolipidic Barrier and Structural Properties. Clin.Pharmacol. Biopharm. 2015, 4, 1000144–1000149.
25.    Micali, G.; Innocenzi, D.; Fabbrocini, G.; Monfrecola, G.; Tosti, A.; Veraldi, S. (Eds.) Le Basi Della Dermatologia Anatomica; Springer Press: New York, NY, USA, 2011.
26.    Panigrahi, B.B.; Panda, P.K.; Patro, V.J. Wound Healing Activity of Spirulina Extracts. Int. J. Pharm. Sci. Rev. Res. 2011,6, 132–135.
27.    If Gur, C.S.; Erdogan, D.K.; Onbasılar, I.; Atilla, P.; Cakar, N. In Vitro and in Vivo Investigations of the Wound HealingEffect of Crude Spirulina Extract and C-Phycocyanin. J. Med. Plants Res. 2013, 7, 425–433.
28.    Gunes, S.; Tamburaci, S.; Dalay, M.C.; Gurhan, I.D. In Vitro Evaluation of Spirulina Platensis Extract Incorporated SkinCream with Its Wound Healing and Antioxidant Activities. Pharm. Biol. 2017, 55, 1824–1832.
29.    Jung, S.-M.; Min, S.K.; Lee, H.C.; Kwon, Y.S.; Jung, M.H.; Shin, H.S. Spirulina-PCL Nanofiber Wound Dressing to ImproveCutaneous Wound Healing by Enhancing Antioxidative Mechanism. J. Nanomater. 2016, 2016, 613Impro
30.    Shehadeh, N.H.; Kligman, A.M. The bacteriology of acne. Arch. Dermatol. 1963, 88, 829.
31.    Kanlayavattanakul, M.; Lourith, N. Therapeutic Agents and Herbs in Topical Application for Acne Treatment. Int. J. Cosmet. Sci. 2011, 33, 289–297.
32.    Gervason, S.; Metton, I.; Gemrot, E.; Ranouille, E.; Skorski, G.; Cabannes, M.; Berthon, J.; Filaire, E. RhodomyrtusTomentosa Fruit Extract and Skin Microbiota: A Focus on C. Acnes Phylotypes in Acne Subjects. Cosmetics 2020, 7, 53.
33.    Nihal, B.; Vishal Gupta, N.; Gowda, D.V.; Manohar, M. Formulation and Development of Topical Anti Acne Formulationof Spirulina Extract. Int. J. Appl. Pharm. 2018, 10, 2
34.    Kumar, V., Bhatnagar, A.K. and Srivastava, J.N. (2011). Antibacterial activity of crude extracts of Spirulina platensis and its structural elucidation of bioactive compound. J Med Plants Res. 5(32): 7043-7048.
35.    Rajasekar, P., Palanisamy, S., Anjali, R., Vinosha, M., Elakkiya, M., Marudhupandi, T. and Prabhu, N. M. (2019). Isolation and structural characterization of sulfated polysaccharide from Spirulina platensis and its bioactive potential: In vitro antioxidant, antibacterial activity and Zebrafish growth and reproductive performance. International J. of Biological Macromolecules, 141, 809-821.

Recomonded Articles:

Author(s): R. R. Shah, S. A. Mohite, N. R. Patel

DOI: 10.5958/2231-5691.2018.00007.2         Access: Open Access Read More

Author(s): AK Meena, MM Rao, RP Meena, P Panda, Renu

DOI:         Access: Open Access Read More

Author(s): Mohite M S, Shelar P A, Raje V N., Babar S. J., Sapkal R. K.

DOI:         Access: Open Access Read More

Author(s): Neha Meshram, Mithlesh Ojha, Ajay Singh, Amit Alexander, Ajazuddin, Mukesh Sharma

DOI: 10.5958/2231-5691.2015.00009.X         Access: Open Access Read More

Author(s): S.K. Purohit, R. Solanki, V. Mathur, M. Mathur

DOI:         Access: Open Access Read More

Author(s): Kavya V. Reddy, Ashish V. Yachawad, Krushna K. Zambare, Sopan Landge

DOI: 10.5958/2231-5691.2020.00016.7         Access: Open Access Read More

Author(s): Vinay C H, Prakash Goudanavar, Ankit Acharya, Mohammed Gulzar Ahmed, Prem Kumar S R

DOI: 10.5958/2231-5691.2018.00012.6         Access: Open Access Read More

Author(s): Gadilohar N. R, Girase A. M, Suryawanshi H. P, Pawar S. P

DOI: 10.5958/2231-5691.2018.00030.8         Access: Open Access Read More

Author(s): Batra Neha, Jain Honey, Bairwa Ranjan, Bachwani Mukesh

DOI:         Access: Open Access Read More

Author(s): Abhijit Ray

DOI:         Access: Open Access Read More

Author(s): P. Muthukumaran, P. Shanmuganathan , C. Malathi

DOI:         Access: Open Access Read More

Author(s): Rangarajan Narasimhan, Sathiyamoorthy. M

DOI: 10.5958/2231-5691.2016.00001.0         Access: Open Access Read More

Author(s): Muhammad Hamza Ashfaq, Amna Siddique, Sammia Shahid

DOI: 10.52711/2231-5691.2021.00021         Access: Open Access Read More

Author(s): Srivastav Sanchit, Luhach Kanishk, Shukla Chhama, Yadav Rajender

DOI:         Access: Open Access Read More

Author(s): Jadhav Sameer S., Salunkhe Vijay R. , Magdum Chandrakant S.

DOI:         Access: Open Access Read More

Author(s): Valli G, Jeyalakshmi M.

DOI:         Access: Open Access Read More

Asian Journal of Pharmaceutical Research (AJPRes.) is an international, peer-reviewed journal, devoted to pharmaceutical sciences. AJPRes. publishes Original Research Articles, Short Communications..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5691 

Recent Articles