Exploring the benefits of Chandraprbha Vati a Herbmineral Formulation
Kanchan Swami, Reetesh Ramnani, Sakhitha K.S., Anupam Srivastava
Department of Rasashastra and Bhaishajya Kalpana, National Institute of Ayurveda,
Deemed to be University (Denovo), Jaipur, Rajasthan, Pincode - 302002, India.
*Corresponding Author E-mail: drkanchanswami@gmail, dr.sakhitha@gmail.com, ritesh.ramnani@gmail.com, dras2011@gmail.com
ABSTRACT:
Chandraprabha Vati, a herb mineral formulation from ancient Ayurvedic texts, exhibits broad-spectrum therapeutic activity. Described in various classical texts, it contains 37 ingredients, predominantly Shilajatu and Guggulu, alongside other key elements like Triphala and Guduchi. Its diverse indications include diabetes, skin disorders, diarrhea, fever and urinary issues. The formulation's mechanism includes rectifying poor digestive fire, addressing lipid metabolism, reducing inflammation, and boosting immunity. Research validates its efficacy in diabetes management and many studies explore its hypoglycemic, hypotensive, and bacteriostatic properties. Chandraprabha Vati holds immense potential in managing lifestyle disorders and urinary ailments when used judiciously.
INTRODUCTION:
The ancient Ayurvedic classics, such as Charaka Samhita, Sushruta Samhita and Ashtanga Hridaya etc. have preserved valuable knowledge about indigenous therapeutics of our country. The relevant work done in the ancient period is majorly focused on herb mineral and herbal formulations. Among the various available herb mineral formulations, Chandraprabha Vati a unique formulation has broad spectrum therapeutic activity. The Formulation has been described in various texts such as Sharanagadhara Samhita, Bhaishajya Ratnavali, Sidha Yoga Sangraha, Yoga Taringani, Yoga Ratnakara, Rasendra Sara Sangraha, Rasendra Chintamani, Vasavvaraziyam and Rasa Ratna Samucchya including Ayurvedic Formulary of India in Prameha (Diabetes).
Indications of Chandraprabha Vati are diverse. It is also recommended for Arsha (Piles) in Rasendra Sara Sangrha, Rasa Kamdhenu, Rasa Chandanshu, Rasendra Chintamani and Vaidya Chintamani, also in Kushtha (Skin disorder) as per Rasa Kamdhenu and in Atisar (Diarrhea) as described Rasa Manjari, Yoga Ratnakara, Vrihat Rasa Raj Sundar and Bharat Bhaishajya Ratnakara. Ayurvedic Formulary of India,1 the official publication of Government of India recognizes the Chandraprabha Vati, as described in Sharanagadhara Samhita.
Methodology:
Chandraprabha Vati, consists of 37 ingredients derived both from plant and mineral sources, serves as a potent option in the treatment of Prameha (Diabetes), Kushtha (Skin disorder), Atisar (Diarrhea), Jwara (Fever), Udararoga (Abdominal disorder), Netraroga (Eye disorder), Dantaroga (Dental disorder) and Gudagata Vyadhi (Ano rectal disorder) etc. as it impacts on the Rasavaha, Raktavaha, Mamsavaha, Medovaha, Shukravaha, Purishavaha, and Mutravaha Srotas of the Human Body System.
Composition of Chandraprabha Vati:
Chandraprabha Vati is a potent herbal medicine with 37 ingredients, each contributing to its effectiveness. Shuddha Shilajatu and Shuddha Guggulu dominate the mix with 32 parts each, followed by Sharkara at 16 parts and Lauha Bhasma at 8 parts. Other ingredients like Trivrita, Dantimoola, Tejpatra, Twak, Ela and Vanshlochana are in quantity of 4 parts each, while the remaining ingredients add up to 1 part each. At its heart lies Chandaprabha (Karpoora), lending its name and essence to the medicine. This rich composition makes Chandraprabha Vati a holistic solution for a wide range of health issues, particularly effective in managing lifestyle disorders. Being an herb mineral compound, its ingredients and properties detailed below contribute to its broad-spectrum therapeutic activity. (Table 1).
Table No.1: Showing the Properties of the ingredients of Chandraprabha Vati
|
Sr. No. |
Drugs |
Rasa |
Guna |
Veerya |
Vipaka |
|
1 |
Chandraprabha |
|
|
|
|
|
Sati (Hedychium spicatum) |
Katu, Tikta, Kashaya |
Laghu, Teekshna |
Ushna |
Katu |
|
|
Karpura (Cinnamomum camphora) |
Tikta, Katu, Madhur |
Laghu, Teekshna |
sheeta |
Madhur |
|
|
Shatavari (Asparagous racemosus) |
Madhur, Tikta |
Guru, Snigdha |
sheeta |
Katu |
|
|
2 |
Vacha (Acorus calamus) |
Katu, Tikta |
Laghu, Teekshna |
Ushna |
Katu |
|
3 |
Musta (Cyperus rotundus) |
Tikta, Katu, Kashaya |
Laghu, Ruksha |
Sheta |
Katu |
|
4 |
Bhunimba (Swertia chiraita) |
Tikta |
Laghu, Ruksha |
Ushna |
Katu |
|
5 |
Guduchi (Tinospora cardifolia) |
Tikta, Kashaya |
Guru, Snigdha |
Ushna |
Madhur |
|
6 |
Devdaru (Cedrus Deodara) |
Laghu, Snigdha |
Tikta |
Ushna |
Katu |
|
7 |
Haridra (Curcuma longa) |
Tikta, Katu |
Ruksha, Laghu |
Ushna |
Katu |
|
8 |
Ativisa (Aconitum heterophyllum) |
Tikta, Katu |
Ruksha, Laghu |
Ushna |
Katu |
|
9 |
Daruharidra (Berberis aristata) |
Tikta, Kashaya |
Ruksha, Laghu |
Ushna |
Katu |
|
10 |
Chitraka (Plumbago zeylanica) |
Katu |
Ruksha, Laghu, Teekshna |
Ushna |
Katu |
|
11 |
Pippalimool (Piper longum) |
Katu |
Laghu, Snigdha, Teekshna |
Unushna Sheeta |
Madhur |
|
12 |
Dhanyaka (Coriandrum sativum) |
Tikta, Kashaya |
Snigdha, Laghu |
Ushna |
Madhur |
|
13 |
Haritaki (Terminalia chebula) |
Pancharasa, (Kasaya Pradhan) |
Ruksha, Laghu |
Ushna |
Madhur |
|
14 |
Aamlaki (Emblica officinalis) |
Pancharasa (Amla Pradhan) |
Ruksha, Sheeta |
Sheeta |
Madhur |
|
15 |
Vibhitak (Terminalia bellirica) |
Kashaya |
Ruksha, Laghu |
Ushna |
Madhur |
|
16 |
Chavya (Piper chaba) |
Katu |
Ruksha, Laghu |
Ushna |
Katu |
|
17 |
Vidanga (Embelia ribes) |
Katu, Kashaya |
Ruksha, Laghu |
Ushna |
Katu |
|
18 |
Gajpippal (Scindapsis officinalis) |
Katu |
Ruksha |
Ushna |
Katu |
|
19 |
Sunthi (Zingiber officinalis) |
Katu |
Laghu, Snigdha |
Ushna |
Madhur |
|
20 |
Marich (Piper nigrum) |
Katu |
Laghu, Teekshna |
Ushna |
Katu |
|
21 |
Pippali (Piper longum) |
Katu |
Laghu, Teekshna |
Unushna, Sheeta |
Madhur |
|
22 |
Trivrita (Operculina turpentum) |
Katu, Tikta |
Laghu, Teekshna |
Ushna |
Katu |
|
23 |
Dantimoola (Boliospermum montanum) |
Katu |
Guru, Teekshna |
Ushna |
Katu |
|
24 |
Tejpatra (Cinnamomum tamala) |
Katu, Tikta, Madhur |
Laghu, Teekshna |
Ushna |
Katu |
|
25 |
Twak (Cinnamomum zeylanicum) |
Katu, Tikta, Madhur |
Laghu, Ruksha, |
Ushna |
Katu |
|
26 |
Ela (Elettaria cardamomum) |
Katu, Madhur |
Laghu, Ruksha |
Sheeta |
Madhur |
|
27 |
Vanshlochana (Bambusa bambos) |
Kasaya, Madhur |
Laghu, Teekshan |
Sheeta |
Madhur |
|
28 |
Shuddha Guggulu (Commiphora mukul) |
Tikta, Katu |
Ruksha, Laghu, Teekshan (P.G.), Snigdha, pichila (N.G.) |
Ushna |
Katu |
|
29 |
Swarnamakshika (Iron Pyrite) |
Tikta, Madhur |
Laghu |
Sheeta |
Katu |
|
30 |
Yavakshara (Potassium carbonate) |
Lavan, Katu |
Laghu, Snigdha, Sukshma |
Ushna |
Katu |
|
31 |
Swarjikshara (Sodium carbonate) |
Lavan, Katu |
Laghu, Teekshna, Ruksha |
Ushna |
Katu |
|
32 |
Saindhava (Sodium chloride) |
Lavan, Madhur |
Laghu, Snigdha |
Sheeta |
Katu |
|
33 |
Souvarchal |
Katu |
Laghu, Sukshma |
Ushna |
Laghu |
|
34 |
Vida lavan |
Lavan |
Laghu, Teekshna |
Ushna |
Katu |
|
35 |
Lauha Bhasma |
Tikta |
Snigdha |
Sheeta |
Katu |
|
36 |
Shuddha Shilajatu (Asphaltum punjabinum) |
Katu, Tikta |
Guru |
Ushna |
Katu |
|
37 |
Sharkara (Sachrum officinerum) |
Madhur |
Guru, Snigdha |
Sheeta |
Madhur |
Madhur-sweet, Amla-sour, Lavan-salt, Katu-pungent, Tikta-bitter, Kasaya-astrigent, Ushna-hot, Sheeta-cool, Guru-heavy, Laghu-light, Snigdha-soft, Ruksha-dry, Teekshna-sharp
DISCUSSION:
In the context of its therapeutic action, the presence of Shilajatu as major ingredient of the formulation, helps to treat dyslipidemia and prevent ischemia.2 The other second major ingredient Guggulu showcases anti-inflammatory properties, making it effective against inflammatory conditions in the genito-urinary tract.3 Chandraprabha Vati having alkaline substances like Yavakshara and Svarjikakshara which reduces urine pH, alleviating burning micturition.4 Ingredients such as Trikatu, Chavya, Musta, Lavana, and Kshara work as to rectify Mandagni (poor digestive fire), considered a fundamental factor in various disease conditions. Furthermore, Chandraprabha Vati also have Triphala5 and Guduchi6, as antioxidants which boosts immunity and serve as immune-modulatory agents in autoimmune and immune-deficient states. Its prevailing actions involve Rakta Prasadana (Blood purifier), Shothahara (Anti-inflammatory), Krimighna (Anti-Bacterial), Mutra virechaka (Diuretics) and Rasayana indicating its efficacy in various conditions.7 Diseases related to Mutra (urine) such as Mutraghata, Mutrakrichhra, and Ashmari find therapeutic application in Chandraprabha Vati.8 Notably, Prameha (Diabetes mellitus) has been substantiated by research studies demonstrating the anti-diabetic activity of Chandraprabha Vati.9
CONCLUSION:
Chandraprabha Vati is a herb mineral formulation which have broad spectrum activity. Considering the potential of the Formulation certain researches had been carried out related to its hypoglycemic, hypotensive and bacteriostatic activities and many Research activities are in pipeline. It could be concluded that this unique formulation bears immense potential to address and manage Prameha and related problems at greater extent, if used judiciously.
CONFLICT OF INTEREST:
There are no conflicts of interest.
REFERENCES:
1. The Ayurvedic Formulary of India, 2nd ed, Govt. of India, Part 1, 2003, Chapter 12, page no.512-515.
2. Gupta G. Bharata Bhaishajya Ratnakara, Commentary. Reprint ed. New Delhi, B. Jain Publisher Pvt. Ltd. 2005: 152-155, 210-211.
3. Kunte AM. Astanga Hridaya, with Arunadatta, Sarvangasundara, Commentary. Reprint ed. Bombay: Nirnaya Sagar Press. 1939. Page no. 236.
4. Bhuvad, Sushama. Pharmaco-Therapeutic Profiles of Chandraprabhavati- An Ayurvedic Herbo-Mineral Formulation. International Journal of Pharmaceutical and Biological Archives. 2012: 1368-1375.
5. Singh R, Singh B, Kumarb N. Antioxidant Activity of Triphala a Combination of Terminalia chebula, Terminalia bellerica And Emblica officinalis. Journal of Food Biochemistry. 2010; 222-232.
6. Desai VR, Kamat JP, Sainis KB. An immunomodulator from Tinospora cordifolia with antioxidant activity in cell free systems. J Chem Sci. 2002; 713–719
7. Weerasekera KR, Ratnasooriya WD, Ranasingha P, Dhammarathana I. Evaluation of Some Therapeutic Effects of Ayurvedic Herbomineral Formulation: Chandraprabha Vati, Annual Research Symposium. 2014; 307-312
8. Gune PG. Ayurvediya Aushadhi Guna Dharma Shastra, Part 3, Delhi; Choukambha Sanskrit Sansthan. 2021: 13.
9. Bagul MS, Srinivasa H, Kanaki NS, Rajani M. Antiinflammatory activity of two Ayurvedic formulations containing guggul. Indian J Pharmacol. 2005; 399-400.
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Received on 13.05.2024 Revised on 05.09.2024 Accepted on 08.11.2024 Published on 17.12.2024 Available online on December 23, 2024 Asian Journal of Pharmaceutical Research. 2024; 14(4):411-413. DOI: 10.52711/2231-5691.2024.00065 ©Asian Pharma Press All Right Reserved
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