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Asian Journal of Pharmaceutical Research
ISSN: 2231-5691(Online), 2231-5683(Print)
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Effect of Wound Healing Potential of Plumeria obtusa (Champa) Spray
Abhishek R. Bura
Abhishek R. Bura*
Dr. Vithalrao Vikhe Patil Foundation’s College of Pharmacy, Vilad Ghat, Ahmednagar- 414001, Maharashtra, India.
Plumeria obtusa is commonly known as Champa (Hindi), White Frangipani (Australia) belonging to family Apocynaceae. The aim of this project is to study the wound healing activity of ethanolic extract of Plumeria obtusa leaves spray. The wound healing activity was studied by the in-vivo method. In Vivo method by excision model the % wound closure rate on the epidermal skin of white Wistar albino rats was studied and was compared with standard Hansaplast spray. In this animals were divided into 4 groups of 5 each. Group 1 was left untreated and considered as control. Group 2 was treated with the standard Hansaplast spray. Group 3 was treated with 5% test Plumeria obtusa spray and group 4 was treated with 10% test Plumeria obtusa spray. In the incision wound model, the tensile strength or skin breaking strength was measured and studied. The tensile strength was measured on the 10th post-wounding day and compared to the control group. The studies carried out in these both experimental models shows that 10% Plumeria obtusa extract spray shows better and efficient wound healing activity than 5% Plumeria obtusa extract spray. The futures expect is to isolate and study the activity of specific chemical constituent responsible for wound healing activity from the Plumeria obtusa leaf extract.
Champa, Plumeria obtusa, Wound contraction rate, Tensile strength, Extract.
Abhishek R. Bura. Effect of Wound Healing Potential of Plumeria obtusa (Champa) Spray. Asian J. Pharm. Res. 2018; 8(4): 231-235.
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