Volume No. :   8

Issue No. :  4

Year :  2018

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Autolysis activity of Vancomycin Resistance Staphylococcus epidermidis



Address:   Mariam K. Abdrabaa1, May T. Flayyih2
1Department of Medical Lab.Technology, Al-Esraa University College
2Department of Biology, College of Science, University of Baghdad. Baghdad, Iraq
*Corresponding Author
DOI No: 10.5958/2231-5691.2018.00038.2

ABSTRACT:
The effect of vancomycin resistant on cell autolysis activity of Staphylococcus epidermidis was detected by whole cell autolytic assay. Three isolates of S. epidermidis, vancomycin sensitive (VSSE), vancomycin resistance (VRSE) and vancomycin intermediate (VISE) were tested. The results revealed that there was significant difference among three isolates, the VSSE isolate (S.epidermidis 22) have the highest autolytic activity in the presence of antibiotic , followed by the VRSE isolate (S. epidermidis 1) and the VISE isolate (S. epidermidis14) which was the lowest autolytic activity with the presence of antibiotic. The result of transmission electron microscope (TEM) showed that the VRSE isolates (S. epidermidis 1) have thicker cell wall followed by VISE (S. epidermidis 14) isolates. However, the VSSE (S. epidermidis 22) didn't showed any cell wall thickening
KEYWORDS:
Staphylococcus epidermidis, vancomycin resistant, autolysin, VRSE, VISE, VSSE.
Cite:
Mariam K. Abdrabaa, May T. Flayyih. Autolysis activity of Vancomycin Resistance Staphylococcus epidermidis. Asian J. Pharm. Res. 2018; 8(4): 225-230.
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