Volume No. :   8

Issue No. :  3

Year :  2018

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Evaluation of In Vitro Anti Inflammatory activity of Kusta Gaja Kesari - A Siddha Herbo Mineral Formulation against Albumin Protein Denaturation



Address:   A. Sureka1*, C. Mary Sharmila2, R. Chithra Devi 3, N. J. Muthu Kumar 4, V. Banumathi5
1Emergency Medical Officer, National Institute of Siddha, Tambaram Sanatorium.
2Resident Medical Officer, National Institute of Siddha, Tambaram Sanatorium.
3House Officer, National Institute of Siddha, Tambaram Sanatorium.
4Associate Professor, Hospital Superintendent, National Institute of Siddha, Tambaram Sanatorium.
5Director, National Institute of Siddha, Tambaram Sanatorium.
*Corresponding Author
DOI No: 10.5958/2231-5691.2018.00025.4

ABSTRACT:
Aim: The present study is conducted to evaluate the In Vitro Anti Inflammatory activity of Kusta Gaja Kesari (KGK) against Protein (Albumin) Denaturation. Methods: The test drug (KGK) at varying concentration ranges from 100 to 500 µg/ml is incubated and heated with Egg albumin in controlled experimental conditions. The percentage inhibition of the protein denaturation is calculated. Diclofenac sodium is used as reference standard drug. Result: The results from the present study clearly indicates that the test drug KGK is effective in inhibiting heat induced protein denaturation. A maximum percentage of inhibition of 51.21 % was observed at 500 µg/ml when compared with the standard.
KEYWORDS:
Anti inflammatory activity, Kusta Gaja kesari, Protein Denaturation Assay, Siddha, Skin diseases.
Cite:
A. Sureka, C. Mary Sharmila, R. Chithra Devi, N. J. Muthu Kumar, V. Banumathi. Evaluation of In Vitro Anti Inflammatory activity of Kusta Gaja Kesari - A Siddha Herbo Mineral Formulation against Albumin Protein Denaturation . Asian J. Pharm. Res. 2018; 8(3): 145-147.
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