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Asian Journal of Pharmaceutical Research
ISSN: 2231-5691(Online), 2231-5683(Print)
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Guidelines for Antibiotic Therapy of Urinary Tract Infection in Acute Pyelonephritis, Bacteriuria in Adolescents
Assistant Professor, Department of Biochemistry, Kongu Arts and Science College, Erode- 638107,
The term Urinary tract infection (UTI) encompasses a broad range of chemical entities that share are characteristics, a positive urine culture. UTI are detected by performing a urine analysis and the confirmed with a urine culture. If there are pathogenic bacteria present, these susceptibility testing is done to make sure that the antibiotic will have good activity against the micro -organism causing infections. The main objective of the present study was the various factors which influence the infection caused by bacteria, analyze the various diagnosis in the different tract infection area, the influence of microbes of media and to offer suggestions for the treatment of UTIs based on the study. Clean-Catch midstream urine of the patients was collected. Urine specimens were cultured for isolation of the microbial agents of UTI. The isolated bacteria were identified using biochemical tests. Disk diffusion susceptibility test was used to determine susceptibility of bacterial agents to antibiotics. Some non-laboratory test also proceed to detect UTIs are 1.Cystoscopy 2. Intravenous pyelogram. The structural abnormalities of GU tract showed the severity of bacterial infection. Chloramphenicol, Amikacin, Oflaxacin, Doxycycline, antibiotics were taken to test the antibiotics sensitivity in the urine samples from UTI infected patients. Among the four antibiotics Chloramphenicol and Doxycyline inhibits the most bacterial strains such as E. Coli, Klebsilla, Staphylococcus aureus and Pseudomonas were more effective. The bacteria in UTI are eradicated with the single dose of antibiotics. Combination therapy is used to treat recurrent infections to inhibit the growth of resistant strains where the effect of combination therapy of antibiotics was greater than the effect of single antibiotics. The cystocope and Pyelogram which are useful in diagnosis of UTI caused structural abnormality of recurrent UTI of bacteriauria.
Urinary tract infection, Antibiotic Susceptibility, Anti-Microbial agents.
N. Sangeetha. Guidelines for Antibiotic Therapy of Urinary Tract Infection in Acute Pyelonephritis, Bacteriuria in Adolescents. Asian J. Pharm. Res. 2018; 8(2): 83-86.
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