Volume No. :   8

Issue No. :  2

Year :  2018

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Development and Characterization of Orange Peel Extract Based Nanoparticles



Address:   Vinay C H1*, Prakash Goudanavar2, Ankit Acharya1, Mohammed Gulzar Ahmed3, Prem Kumar S R4
1,2Research Scholar, Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka -571 448.
3Professor and Principal, Yenepoya College and Research centre, Yenepoya University, Mangalore -575 018.
4JRF, Novel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, SETs College of Pharmacy, S R Nagara, Dharwad, Karnataka-580002
*Corresponding Author
DOI No: 10.5958/2231-5691.2018.00012.6

ABSTRACT:
The main objective of the present work was to prepare orange peel extract based nano particles by chemical complexation method. Ethanolic extracts of orange peel were prepared by using Soxhlet apparatus and evaluated for phyto-chemical constituents. Qualitative analysis showed that orange peel extract showed positive results for alkaloids, tannin and saponins. The percentage moisture content and pH of the extract was found to be 96.1% and 3.8 respectively. A zeta potential and particle size of prepared nanoparticles was found in the range of – 32.0 mV to -21.4 mV and 178.8 nm to 191.6 nm, respectively. These range confirms that obtained particles were in nano range, i.e. <500 nm size. SEM results indicated the formation of nanoparticles and were relatively spherical in shape. Energy dispersive spectrometry (EDS) analysis confirms the presence of AgNPs. Further the study will be extended for anti-microbial and wound healing activities.
KEYWORDS:
Pomegranate peel extract, Qualitative analysis, Nano particles.
Cite:
Vinay C H, Prakash Goudanavar, Ankit Acharya, Mohammed Gulzar Ahmed, Prem Kumar S R. Development and Characterization of Orange Peel Extract Based Nanoparticles. Asian J. Pharm. Res. 2018; 8(2): 71-77.
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