Volume No. :   7

Issue No. :  2

Year :  2017

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Anti-Inflammatory activity of Ethanolic extract of Basella alba in acute and Sub-acute Model



Address:   Naidu Narapusetty1*, O. Sivaiah1, B. Balanasaraiah1, M. Haranadhbabu, B. Prasad1, B. Hosanna Crown1, Ch. M. M. Prasada Rao2
1Department of Pharmacology, Bellamkonda Institute of Technology and Sciences, Podili
2Department of Pharm. Chemistry, QIS College of Pharmacy, Ongole
*Corresponding Author
DOI No: 10.5958/2231-5691.2017.00015.6

ABSTRACT:
The present study is carried out to investigate the anti-inflammatory potential of Ethanolic extract of Basella alba (BA). Anti-inflammatory activity was evaluated by using Egg Albumin, Turpentine Oil and Formaldehyde as phlogistic agents. The animals were treated with doses 250mg/kg and 500mg/kg of extract and Diclofenac Sodium at a dose of 10mg/kg is used as a standard drug. The BA showed a significant anti-inflammatory activity in a dose dependent manner in all the models when compared with the standard treatment. The extract (500mg/kg) exhibited maximum antiinflammatory activity i.e., 46.25%, 44.30%, 46.40% (P<0.001) like standard Diclofenac 47.02%, 46.50%, 48.57% in Egg albumin, Turpentine oil and Formaldehyde induced methods respectively. Based on the above results, we conclude that the BA has significant anti-inflammatory activity and might prove efficacious for further design and development of agents with significant biological activity.
KEYWORDS:
Basella alba, anti-inflammatory activity, phlogistic agents.
Cite:
Naidu Narapusetty, O. Sivaiah, B. Balanasaraiah, M. Haranadhbabu, B. Prasad, B. Hosanna Crown, Ch. M. M. Prasada Rao. Anti-Inflammatory activity of Ethanolic extract of Basella alba in acute and Sub-acute Model. Asian J. Pharm. Res. 2017; 7(2):88-93.
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