Volume No. :   7

Issue No. :  1

Year :  2017

ISSN Print :  2231-5683

ISSN Online :  2231-5691


Registration

Allready Registrered
Click to Login

A Review- Ceftriaxone for Life



Address:   Mohd. Yaqub Khan*, Maryada Roy, Raj Kumar Rawal, Umesh Kumar Bansal
Prosperity 6 Pharmaceutics, Plot No. 23, EPIP Phase 2, Thana, Baddi, Himachal Pradesh-173205, India
*Corresponding Author
DOI No: 10.5958/2231-5691.2017.00007.7

ABSTRACT:
Ceftriaxone for injection, USP is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration. Ceftriaxone sodium is (6R, 7R)-7-[2-(2-Amino-4-thiazolyl) glyoxylamido]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio]methyl]-5-thia-1-zabicyclo [4.2.0] oct-2-ene-2-carboxylic acid, 72-(Z)-(O-methyloxime), disodium salt, sesquaterhydrate. Ceftriaxone is a third-generation of cephalosporins which is used for community acquired infections such as pneumonia and urinaly tract infections. It showed great advantage of once-daily administration based on pharmacological manner and need no renal impairment. It is stable for ß-lactamases against first- or second- generations of cephalosporins. Ceftriaxone is also used for streptococcal endocarditis as alternative first-line therapeutic regimen and used for Sexually Transmited Disease (STD) such as syphilis and chancoroid.
KEYWORDS:
Ceftriaxone, Cephalosporin, β-lactamases
Cite:
Mohd. Yaqub Khan, Maryada Roy, Raj Kumar Rawal, Umesh Kumar Bansal. A Review- Ceftriaxone for Life. Asian J. Pharm. Res. 2017; 7(1): 35-48.
[View HTML]     



Visitor's No. :   25626