Volume No. :   6

Issue No. :  3

Year :  2016

ISSN Print :  2231-5683

ISSN Online :  2231-5691


Registration

Allready Registrered
Click to Login

Docking of Hematoporphyrin on Various Anticancer Drugs Targeting Enzymes



Address:   Nandhini S1*, Radha R 2, Vadivu R3
1PG Scholar, Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai, India
2Professor & Head of the Department, Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai, India
3Assiatant Professor, Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai, India.
*Corresponding Author
DOI No: 10.5958/2231-5691.2016.00019.8

ABSTRACT:
The present study deals with docking of Hematoporphrin with various anticancer drugs targeting enzymes. The targets used were PDB-ID 2Y3I, PDB-ID 3OZZ, PDB-ID 3UEN and PDB-ID 4O33. Hematoporphyrin docked with these enzymes and interactions between the enzyme and compound were measured and compared with standard Paclitaxel. The study concluded that, the compound (Hematoporphyrin) isolated from plant were high interactions with PDB-ID 4O33 when compared to standard.
KEYWORDS:
Docking, Hematoporphyrin, Paclitaxel, Protein Data Bank, interactions.
Cite:
Nandhini S, Radha R , Vadivu R. Docking of Hematoporphyrin on Various Anticancer Drugs Targeting Enzymes. Asian J. Pharm. Res. 2016; 6(3): 123-130.
[View HTML]      [View PDF]



Visitor's No. :   98780