Volume No. :   5

Issue No. :  2

Year :  2015

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Evaluation of In Vitro Anti- Inflammatory Activity of Tephrosia purpurea (Seed)



Address:   A. Anbarasi, R. Vidhya*
Department of Biochemistry, Dharmapuram Ganambigai Govt. Arts College (W), Mayiladuthurai-609001. Tamilnadu, India.
*Corresponding Author
DOI No: 10.5958/2231-5691.2015.00012.X

ABSTRACT:
Tephrosia purpurea seed is a valuable medicinal shrubby and woody plant which has been valued for centuries in ayurvedic medicine. Phyto-chemical analysis of aqueous, ethyl acetate and hexane T. purpurea seed extracts revealed the presence of various bioactive phytochemical compounds in all three extracts. The study was aimed to evaluate the anti inflammatory activity of different extracts of T. purpurea by HRBC membrane stabilization and protein denaturation method. The result showed aqueous extract of T. purpurea highest membrane stabilizing activity (85.6± 9.48) and protein inhibition activity (73.1± 8.78) at the concentration of 500 µg, when compared to diclofenac sodium. The result obtained from this study suggests that plant is may be a good natural source for anti-inflammatory therapy.
KEYWORDS:
Tephrosia purpurea, phytochemical analysis, Anti-inflammatory, HRBC, Protein denaturation.
Cite:
A. Anbarasi, R. Vidhya. Evaluation of In Vitro Anti- Inflammatory Activity of Tephrosia purpurea (Seed). Asian J. Pharm. Res. 5(2): April-June 2015; Page 83-89.
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