Volume No. :   3

Issue No. :  4

Year :  2013

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Design, Synthesis and anti microbial, anti-inflammatory, Antitubercular activities of some 2,4,5-trisubstituted imidazole derivatives.



Address:   R. S. Kalkotwar1* and R. B. Saudagar2
1Department of Pharmaceutical Sciences, Bhagwant University, Ajmer, Rajashthan, India
2Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Nashik, M.S. India.
*Corresponding Author
DOI No:

ABSTRACT:
A Novel Series of Some 2,4,5-trisubstituted imidazole derivatives were prepared with the aim to get better antibacterial activity, antifungal activity, antitubercular and anti-inflammatory activity. The structures of synthesized compounds were supported by means of IR, 1H NMR. Title compounds were evaluated for antibacterial activity, antifungal activity, antitubercular and anti-inflammatory activities. Among the synthesized compounds some compounds found to possess all these activities. The QSAR study for anti-inflammatory activity shows good results.
KEYWORDS:
QSAR, Antibacterial, antifungal, anti-inflammatory activity.
Cite:
R. S. Kalkotwar, R. B. Saudagar. Design, Synthesis and anti microbial, anti-inflammatory, Antitubercular activities of some 2,4,5-trisubstituted imidazole derivatives. Asian J. Pharm. Res. 3(4): Oct. - Dec.2013; Page 159-165.
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