Volume No. :   2

Issue No. :  2

Year :  2012

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Hepatoprotective Activity of Aqueous Extract of Lawsonia inermis against Paracetamol Induced Rats



Address:   R. Selvanayaki and T. Ananthi*
PG Department of Biochemistry, S.T.E.T Women’S College, Mannargudi.- 614 001
*Corresponding Author
DOI No:

ABSTRACT:
The present study was conducted to evaluate the hepatoprotective activity of aqueous extract of Lawsonia inermis against paracetamol induced liver damage in rats. The aqueous extract of Lawsonia inermis was administered orally to the animals with hepatotoxicity induced by paracetamol. Silymarin was given as reference standard. The plant aqueous extract was effective in protecting the liver against the injury induced by Paracetamol in rats. This was evident from significant reduction in serum enzymes alkaline aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), Acid Phosphatase (ACP), Protein and Bilirubin. It was concluded from the result that the aqueous extract of Lawsonia inermis possesses hepatoprotective activity against paracetamol induced hepatotoxicity in rats.
KEYWORDS:
Lawsonia inermis, Paracetamol, hepatoprotective and hepatotoxicity.
Cite:
R. Selvanayaki, T. Ananthi. Hepatoprotective Activity of Aqueous Extract of Lawsonia inermis against Paracetamol Induced Rats. Asian J. Pharm. Res. 2(2): April-June 2012; Page 75-77.
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