Volume No. :   1

Issue No. :  4

Year :  2011

ISSN Print :  2231-5683

ISSN Online :  2231-5691


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Antimicrobial Effect of Separate Extract of Acetone, Ethyl Acetate, Methanol and Aqueous from Leaf of Milkweed (Calotropis gigantea L.)



Address:   M. Hemalatha1, B. Arirudran1, A. Thenmozhi1 and U.S. Mahadeva Rao2*
1P.G. Department of Biochemistry, SRM Arts and Science College, Kattankulathur, Kanchipuram District, TamilNadu - 603203, India .
2Associate Professor, Faculty of Medicine and Health Science, Universiti Sultan Zainal Abidin, Kampus Kota, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Terengganu, Malaysia.
*Corresponding Author
DOI No:

ABSTRACT:
Objective: The present communication attempts to study the antimicrobial activity of leaf of Calotropis gigantea L. Methods: The leaf is subjected to various extraction using acetone, ethyl acetate, methanol and aqueous solvents against different bacterial and fungal organisms using disc diffusion method. Result: The acetone, ethyl acetate, methanol and aqueous extracts were active against all the samples and showed significant antibacterial properties. The methanol, acetone, ethyl acetate and aqueous extracts exhibited less activity against fungal organisms. Conclusion: Thus it may be suggested that leaf extracts of Calotropis gigantea L. may be used to treat oral bacterial diseases.
KEYWORDS:
Calotropis gigantea L, Antimicrobial activity, Disc diffusion method.
Cite:
M. Hemalatha, B. Arirudran, A. Thenmozhi, U.S. Mahadeva Rao. Antimicrobial Effect of Separate Extract of Acetone, Ethyl Acetate, Methanol and Aqueous from Leaf of Milkweed (Calotropis gigantea L.). Asian J. Pharm. Res. 1(4): Oct. - Dec. 2011; Page102-107.
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